ReviewCureus2022
Association Between Type 1 Diabetes Mellitus and Celiac Disease: Autoimmune Disorders With a Shared Genetic Background.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Type 1 Diabetes Mellitus Pathogenesis: Mechanisms, Early Diagnostic Strategies, and Emerging Therapeutic Approaches.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Unlocking beta cell health: The clinical potential of extracellular vesicles in type 1 diabetes.Clinical and translational medicine · 2026Review
- Endocrine Autoimmunity and Inflammatory Signatures in Pediatric Celiac Disease: Context-Dependent Patterns.Diagnostics (Basel, Switzerland) · 2026Article
- Early Detection of Pediatric Type 1 Diabetes: The Expanding Role of Screening.Children (Basel, Switzerland) · 2026Review
- Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes.Diabetes/metabolism research and reviews · 2026Review
- Prevalence of autoimmune comorbidities and association with glycemic control by CGM-derived parameters in type 1 diabetes.Endocrine · 2025Article
- Article
- Autoimmune Type 1 Diabetes in the Era of Disease-Modifying Immune Therapy.Diabetes/metabolism research and reviews · 2025Review
- Impact of Climate Change on the Composition and Bioactivity ofFood science & nutrition · 2025Article
- Evaluation of Nailfold Capillaroscopic Findings in Pediatric Patients with Celiac Disease: A Cross-Sectional and Comparative Study.Diagnostics (Basel, Switzerland) · 2025Article
- Risk of new-onset type 1 diabetes in individuals with celiac disease and thyroid disease-An observational study.Diabetes, obesity & metabolism · 2025Observational
- Navigating the crossroads: exploring the intersection of celiac disease and Budd-Chiari syndrome - insights, challenges, and management strategies.Annals of medicine and surgery (2012) · 2025Review
- Bridging the Gap: Awareness, Knowledge, and Challenges of Living with Celiac Disease in Bulgaria.Nutrients · 2025Article
- Assessment of Knowledge of Celiac Disease and Associated Conditions Among Dietitians in Jordan.International journal of environmental research and public health · 2025Article
- The combination effect of treadmill exercise and valerian hydroalcoholic extract on the heart of type 2 diabetic rats.Annals of medicine and surgery (2012) · 2025Article
- Association of celiac disease with type 1 diabetes: A cross-sectional analysis in 2022.Caspian journal of internal medicine · 2025Article
- Expecting factors for inadequate glycemic control in children and adolescents with type 1 diabetes mellitus: a single center experience.Journal of diabetes and metabolic disorders · 2024Article
- Celiac disease autoimmunity among Nigerian children and adolescents with type 1 diabetes mellitus.BMC gastroenterology · 2024Article
- Intestinal microbiome as a diagnostic marker of coronary artery disease: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- The role of gut microbiota augmentation in managing non-alcoholic fatty liver disease: an in-depth umbrella review of meta-analyses with grade assessment.Annals of medicine and surgery (2012) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are one of the most recognized related autoimmune disorders as they share a common genetic background that has been found in the HLA genotype, more specifically DQ2 and DQ8 molecules. Studies have shown that environmental factors as early or late exposure to cereals in the first months of life or the acquired viral infections have been implicated in the risk of development of autoantigens. CD, in most cases, is asymptomatic; therefore, it goes underdiagnosed. As a result, it has been linked to late consequences as decreased growth, delayed puberty, and anemia. Also, CD has been considered an independent risk factor for nephropathy and retinopathy. Therefore, in T1DM patients, as high-risk individuals, a CD screening has been recommended, especially to analyze their joint management. A gluten-free diet has been studied and linked to possible benefits in glycemic control or decreasing the hypoglycemic episodes in T1DM and preventing in CD the late bowel mucosal damage as gluten has been well documented as the primary trigger of these autoimmune responses. This article has reviewed the concurrent occurrence of T1DM and CD regarding the pathogenesis, clinical overlaps, screening, and management options.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.