Evidence map›Paper›PMID 35399374›Full record

ArticleHeliyon2022

Unique peptide signatures of SARS-CοV-2 virus against human proteome reveal variants' immune escape and infectiveness.

Vasileios Pierros, Evangelos Kontopodis, Dimitrios J Stravopodis, George Th Tsangaris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. A survey of k-mer methods and applications in bioinformatics.Computational and structural biotechnology journal · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Vasileios PierrosProteomics Research Unit, Biomedical Research Foundation of the Academy of Athens, 11527, Athens, Greece.
Evangelos KontopodisProteomics Research Unit, Biomedical Research Foundation of the Academy of Athens, 11527, Athens, Greece.
Dimitrios J StravopodisSection of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens, 15701, Athens, Greece.
George Th TsangarisProteomics Research Unit, Biomedical Research Foundation of the Academy of Athens, 11527, Athens, Greece.
Biomedical Research Foundation of the Academy of Athens · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 pandemic has necessitated the identification of sequence areas in the viral proteome that are capable to serve as antigenic sites and treatment targets. In the present study, we have applied a novel approach for mechanistically illuminating the virus-host organism interactions, by analyzing the Unique Peptides (UPs) of the virus featured by a minimum amino acid sequence length being defined as Core Unique Peptides (CrUPs), not of the virus

Indexed as

Core unique peptideCovid-19Delta variantImmune escapeNF9 peptideSARS-CoV-2Spike proteinUniquome

Identifiers

PMID35399374
PMCPMC8979629
OpenAlexW4225497933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.