SynthesisFrontiers in human neuroscience2022
The Effects of Combined Cognitive-Physical Interventions on Cognitive Functioning in Healthy Older Adults: A Systematic Review and Multilevel Meta-Analysis.
Synthesis in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Comparative Efficacy of Non-Pharmacological Multicomponent Interventions in Community-Dwelling Older Adults With Frailty or Prefrailty: A Systematic Review and Network Meta-Analysis.International journal of older people nursing · 2026Pooled it
- The effect of combined motor and cognitive rehabilitation on motor performance in Parkinson's disease: a systematic review and meta-analysis.Journal of rehabilitation medicine · 2026Pooled it
- Individual sedentary activities and cognitive function in middle-aged and older adults: A systematic review.Journal of Alzheimer's disease : JAD · 2026Pooled it
- Evaluating the cognitive impact of exergames on community-dwelling older adults beyond laboratory settings: a systematic review and meta-analysis.Frontiers in dementia · 2026Pooled it
- Effects of aerobic exercise on executive function among overweight and obese children: a systematic review and meta-analysis.Frontiers in psychology · 2024Pooled it
- Effects of motor-cognitive training on dual-task performance in people with Parkinson's disease: a systematic review and meta-analysis.Journal of neurology · 2023Pooled it
- Trial
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- Investigation of the effects of different rehabilitation approaches in elderly individuals with mild cognitive impairment.BMC geriatrics · 2026Trial
- Can dual-task high-velocity exercise training improve cognitive function in older adults? Secondary analysis of an 18-month cluster randomized controlled trial.Age and ageing · 2026Trial
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- Incorporated vs Additional Dual-Task Training in Community-Dwelling Older Adults.Clinical interventions in aging · 2026Trial
- A study on Mahjong intervention to improve cognitive impairment in patients with schizophrenia: a pilot, single-blind, randomized, controlled trial.BMC psychiatry · 2025Trial
- Educational intervention for mental health and health behaviors in elderly Iranian women randomized controlled trial.Scientific reports · 2025Trial
- Optimizing Cognitive and Physical Gains in Older Adults: Benefits of a Psychomotor Intervention Program Based on Functional Level.Medicina (Kaunas, Lithuania) · 2025Trial
- Effects of home-based exercise with or without cognitive training on cognition and mobility in cardiac patients: A randomized clinical trial.GeroScience · 2025Trial
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- Comparative effects of cognitive and instability resistance training versus instability resistance training on balance and cognition in elderly women.Scientific reports · 2024Trial
- "Brain-IT": Exergame training with biofeedback breathing in neurocognitive disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Trial
- Effects of combined dietary intervention and physical-cognitive exercise on cognitive function and cardiometabolic health of postmenopausal women with obesity: a randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2024Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research has shown that both physical exercise and cognitive training help to maintain cognition in older adults. The question is whether combined training might produce additive effects when the group comparisons are equated in terms of exercise intensity and modality. We conducted a systematic electronic search in MEDLINE, PsycInfo, and Cochrane Central Register of Controlled Trials (CENTRAL) databases to identify relevant studies published up to February 2021. Seven hundred and eighty-three effect sizes were obtained from 50 published intervention studies, involving 6,164 healthy older adults, and submitted to a three-level meta-analysis. Results showed that combined training produced a small advantage in comparison to single cognitive training on executive functions, whereas both types of training achieved similar effects on attention, memory, language, processing speed, and global cognition. Combined training achieved higher training gains in balance than single physical training, indicating a transfer from cognitive training to balance. Performing cognitive and physical exercise simultaneously, and interactive training (e.g., exergames, square stepping) produced the largest gains in executive functions, speed, and global cognition, as well as the largest improvements in physical functions. Aerobic training was associated with higher effects in attention and fitness, whereas non-aerobic training produced larger effects in global cognition and balance. For all cognitive and physical outcomes, training resulted more advantageous when performed in a social context, even though individual training obtained similar results in balance as group training.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.