Evidence map›Paper›PMID 35399323›Full record

ArticlePolyhedron2022

Synthesis, characterized, QSAR studies and molecular docking of some phosphonates as COVID-19 inhibitors.

Khodayar Gholivand, Azam Barzegari, Fahimeh Mohammadpanah, Rouhollah Yaghoubi, Roohollah Roohzadeh, Ali Asghar Ebrahimi Valmoozi

Abstract read
In one paragraph

Article in Polyhedron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khodayar GholivandDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Azam BarzegariDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Fahimeh MohammadpanahDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Rouhollah YaghoubiDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Roohollah RoohzadehDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Ali Asghar Ebrahimi ValmooziDepartment of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global coronavirus (COVID-19) outbreak has prompted scientists to discover a cure for the disease. So far, phosphorus-based drugs have been proposed. These drugs have good inhibitory activity against the main protease (Mpro). Hence, in order to introduce a group of inhibitors the coronavirus, 51 compounds containing different mono, bis, and tetra phosphonates as Remdesivir derivatives, 32 of which are new, were synthesized and characterized by

Indexed as

Coronavirus inhibitorsDFT calculationDockingPhosphonate derivativesQSAR

Identifiers

PMID35399323
PMCPMC8978535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.