Evidence map›Paper›PMID 35399182›Full record

ArticleCancer diagnosis & prognosis

Combination of Pembrolizumab With Platinum-containing Chemotherapy for Pulmonary Enteric Adenocarcinoma.

Shuhei Teranishi, Chihiro Sugimoto, Hirokazu Nagayama, Wataru Segawa, Atsushi Miyasaka, Shuntaro Hiro, Chihiro Maeda, Hironori Tamura, Nami Masumoto, Yoshinori Nagahara and 5 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Definitive (chemo)radiotherapy of enteric-type adenocarcinoma of the lung: time to unmask an underrated treatment option?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Shuhei TeranishiRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Chihiro SugimotoRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Hirokazu NagayamaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Wataru SegawaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Atsushi MiyasakaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Shuntaro HiroRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Chihiro MaedaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Hironori TamuraRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Nami MasumotoRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Yoshinori NagaharaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Nobuyuki HiramaRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Nobuaki KobayashiDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Masaki YamamotoRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Makoto KudoRespiratory Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Takeshi KanekoDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yokohama City University · JPYokohama City University Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: Pulmonary enteric adeno-carcinoma (PEAC) is a rare type of non-small cell lung cancer (NSCLC), for which no established standard treatment exists. Combination therapy with the anti-programmed cell death protein 1 antibody pembrolizumab and platinum-containing chemotherapy is the standard treatment for NSCLC patients, but its effectiveness in PEAC is uncertain. Case Report: We present a 68-year-old man with chemotherapy-naïve advanced PEAC who responded to a combination of pembrolizumab and platinum-containing chemotherapy. Conclusion: The number of PEAC cases is small, and no clinical trials have been conducted to determine an optimal chemotherapy regimen. In this case, we showed that pembrolizumab combined with platinum-containing chemotherapy might effectively treat PEAC.

Indexed as

combination chemotherapyimmune checkpoint inhibitorpembrolizumabPulmonary enteric adenocarcinoma

Identifiers

PMID35399182
PMCPMC8962809
OpenAlexW4214493815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.