Evidence map›Paper›PMID 35399169›Full record

ArticleCancer diagnosis & prognosis

Worse Prognosis in the Symptomatic Patients With Lung Cancer - Czech Multicentric Study.

Miloslav Marel, Zdenka Chladkova, Luis Fernando Casas Mendez, Ondrej Venclicek, Jana Skrickova, Ondej Fischer, Andrea Mullerova, Libor Havel, Zuzana Gyorfy, Michal Hrnciarik and 7 more

Abstract read
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Miloslav MarelDepartment of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Zdenka ChladkovaDepartment of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Luis Fernando Casas MendezDepartment of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Ondrej VenclicekDepartment of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital, Brno, Czech Republic.
Jana SkrickovaDepartment of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital, Brno, Czech Republic.
Ondej FischerDepartment of Respiratory Medicine, University Hospital, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
Andrea MullerovaDepartment of Respiratory Medicine, University Hospital, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
Libor HavelDepartment of Respiratory Medicine, Thomayer Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
Zuzana GyorfyDepartment of Respiratory Medicine, Thomayer Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
Michal HrnciarikPulmonary Department, University Hospital, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.
Michal JirousekPulmonary Department, University Hospital, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.
Jana KrejciDepartment of Pneumology, Bulovka University Hospital, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic.
Daniel KrejciDepartment of Pneumology, Bulovka University Hospital, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic.
Marcela BuresovaDepartment of Pneumology and Phthiseology, University Hospital, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Jana AlahakoonOAKS Consulting Praha, Prague, Czech Republic.
Michal SvobodaInstitute of Biostatistics and Analyses, Ltd., Brno, Czech Republic.
Martin SvatonDepartment of Pneumology and Phthiseology, University Hospital, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: This study aimed at contributing to a better diagnosis of lung cancer by analyzing the patient's symptoms and their linkage to other characteristics. Patients and Methods: We analyzed the data of 3,322 patients from LUCAS (LUngCAncerfocuS) National Registry of the Czech Republic. Overall survival was assessed using the Kaplan-Meier method. Results: The most common symptoms were cough (47.5%), dyspnea (45.6%), pain (27.3%), and weight loss (25.7%). Among all patients, 16% were asymptomatic. We demonstrated the negative prognostic significance of increasing number of lung cancer symptoms, that was significant after adjustment for age, TNM stages, and performance status, and morphological types of the cancer. Conclusion: Monitoring the severity and type of symptoms in patients with lung cancer can help in the diagnostics of the disease and the estimation of prognosis.

Indexed as

coughdyspnoeafeverhemoptysisLung cancerprognosissymptomsweight loss

Identifiers

PMID35399169
PMCPMC8962806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.