Evidence map›Paper›PMID 35399167›Full record

ArticleCancer diagnosis & prognosis

Impact of Regional Lymph Node Irradiation on Reducing Lymph Node Recurrence in Esophageal Cancer Patients.

Shigenobu Watanabe, Ichiro Ogino, Daisuke Shigenaga, Masaharu Hata

Open access · greenAbstract read
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shigenobu WatanabeDepartment of Radiation Oncology, Yokohama City University Medical Center, Yokohama, Japan.
Ichiro OginoDepartment of Radiation Oncology, Yokohama City University Medical Center, Yokohama, Japan.
Daisuke ShigenagaDepartment of Radiation Oncology, Yokohama City University Medical Center, Yokohama, Japan.
Masaharu HataDepartment of Radiation Oncology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Yokohama City University · JPYokohama City University Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: To evaluate the preventive effects of regional lymph node irradiation on lymph node recurrence in esophageal cancer (EC). Patients and Methods: The study included 289 patients who received definitive radiotherapy for EC. The regional lymph node area of group 1 was determined as the area with the highest probability of lymph node metastasis and group 2 was determined as the area with the next highest probability of lymph node metastasis depending on the primary site of EC. Results: The patients in whom group 2 was completely included in the irradiated field had a significantly lower rate of recurrence of regional lymph node metastasis than those in whom group 2 was not or insufficiently included (p=0.0337). There was no significant difference in overall survival (p=0.4627) or disease-specific survival (p=0.6174) between the two groups. Conclusion: Regional lymph node irradiation did not have survival-prolonging effects but significantly reduced regional lymph node recurrence.

Indexed as

adverse eventsEsophageal cancerpreventative irradiationregional lymph node recurrence

Identifiers

PMID35399167
PMCPMC8962802
OpenAlexW4214637623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.