Evidence map›Paper›PMID 35399099›Full record

ArticleJournal of orthopaedic surgery and research2022

Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma.

Qiang Huang, YiBo Xu, Yao Lu, Cheng Ren, Lu Liu, Ming Li, Qian Wang, Zhong Li, HanZhong Xue, Kun Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Observational
  5. Article
  6. Article
  7. New bone formation using antibiotic-loaded calcium sulfate beads in bone transports for the treatment of long-bone osteomyelitis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qiang Huang *Department of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
YiBo Xu *Department of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Yao Lu *Department of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Cheng RenDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Lu LiuDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Ming LiDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Qian WangDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Zhong LiDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
HanZhong XueDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China.
Kun ZhangDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China. gukezhangk@163.com.
Teng MaDepartment of Orthopaedic Surgery, Hong Hui hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710054, Shaanxi, China. gukemt@163.com.
Xi'an Jiaotong University · CNXi'an Honghui Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this paper was to compare the clinical effects of acute shortening and re-lengthening (ASR) technique with antibiotic calcium sulfate-loaded bone transport (ACSBT) technique for the management of large segmental tibial defects after trauma.

methodsIn this retrospective study, 68 patients with large segmental tibial defects were included and completely followed. The bone loss was 3-10 cm. ASR group included 32 patients, while ACSBT group contained 36. There was no significant difference in demographic information between the two groups. The external fixation time (EFT) and external fixation index (EFI) were compared. Bone defect healing and limb functions were evaluated according to the Association for the Study and Application of the Method of Ilizarov (ASAMI) criteria. Complications were compared by Paley classification.

resultsThe mean EFT was 9.2 ± 1.8 months in ASR group and 10.1 ± 2.0 months in ACSBT group, respectively. The mean EFI was 1.5 ± 0.2 month/cm and 1.4 ± 0.3 month/cm. According to the ASAMI criteria, in ASR group bone defect healing was excellent in 22 cases, good in 7 cases and fair in 3 cases. In ACSBT group, it was excellent in 23 cases, good in 11 cases and fair in 2 cases. In ASR group, the limb function was excellent in 15 cases, good in 7 cases and fair in 10 cases, while it was excellent in 14 cases, good in 9 cases and fair in 13 cases with ACSBT group. There was no significant difference in EFI, bone defect healing and limb functions between the two groups (p > 0.05). The mean number of complications per patient in ACSBT group was significantly lower than that in ASR group (p < 0.05).

conclusionBoth techniques can be successfully used for the management of large segmental tibial defects after trauma. There was no significant difference in EFI, limb functions and bone defect healing between the two groups. Compared with ASR group, the complication incidence in ACSBT group was lower, especially the infection-related complications. Therefore, for patients with large segmental bone defects caused by infection or osteomyelitis, ACSBT technique could be the first choice.

Indexed as

Ilizarov TechniqueTibial FracturesAnti-Bacterial AgentsCalciumCalcium SulfateExternal FixatorsHumansRetrospective StudiesSulfatesTibiaTreatment OutcomeAnti-Bacterial AgentsCalciumCalcium SulfateSulfatesAcute shorteningBone transportCalcium sulfateTibial defect

Identifiers

PMID35399099
PMCPMC8996420
OpenAlexW4223453035

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.