Evidence map›Paper›PMID 35398628›Full record

ArticleSleep medicine2022

Clinical characterization of insomnia in adolescents - an integrated approach to psychopathology.

Dilara Yuksel, Orsolya Kiss, Devin E Prouty, Fiona C Baker, Massimiliano de Zambotti

Open access · greenAbstract read
In one paragraph

Article in Sleep medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stress, hypothalamic pituitary adrenal axis activity and autonomic nervous system function in adolescents with insomnia.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Dilara YukselCenter for Health Sciences, SRI International, Menlo Park, CA, USA.
Orsolya KissCenter for Health Sciences, SRI International, Menlo Park, CA, USA.
Devin E ProutyCenter for Health Sciences, SRI International, Menlo Park, CA, USA.
Fiona C BakerCenter for Health Sciences, SRI International, Menlo Park, CA, USA; Brain Function Research Group, School of Physiology, University of the Witwatersrand, Johannesburg, South Africa.
Massimiliano de ZambottiCenter for Health Sciences, SRI International, Menlo Park, CA, USA. Electronic address: massimiliano.dezambotti@sri.com.
SRI International · US

Funding

Sleep and Cardiovascular Health in AdolescenceR01HL139652 · NHLBI · SRI INTERNATIONAL · PI DE ZAMBOTTI, MASSIMILIANO · 2018 to 2021
$2.9M
NHLBI NIH HHS R01 HL139652
6 · The paper itself

Abstract

OBJECTIVES/

backgroundInsomnia in adolescence is common and debilitating yet it remains poorly understood. Here, we examine the complexity of clinical, behavioral, and psychosocial factors characterizing insomnia in adolescents.

methodsNinety-five adolescents (16-19 years) with (N = 47, 31 female) and without (N = 48, 28 female) insomnia symptoms participated. In the insomnia group, 26 (20 female) met full DSM-5 criteria for insomnia disorder, while 21 (11 female) met partial criteria. Participants completed a clinical interview and assessments of clinical, behavioral, and psychosocial dimensions associated with insomnia. GLMs and network analyses were used to evaluate group and sex differences in severity and inter-relationships between symptoms.

resultsAdolescents with insomnia symptomatology had lower sleep hygiene and thought control, more depressive symptoms and dysfunctional sleep-related cognitions, and more substance use as a coping behavior than healthy controls. They also indicated higher neuroticism, stress levels, and sleep stress reactivity (p < 0.05), but no difference in adverse childhood experiences, than controls. Girls compared to boys with insomnia reported lower sleep quality, and more pre-sleep cognitive activity and sleep stress reactivity (p < 0.05). Compared to healthy girls, girls in the insomnia group reported lower sleep hygiene and higher agreeableness. Network analyses confirmed profound group differences in network topology, with the insomnia group having different levels of centrality and relationships between clinical characteristics compared with controls.

conclusionsFindings highlight clinical and sex-specific characteristics of adolescent insomnia, with network analyses revealing a complex interplay between clinical, behavioral, and psychosocial domains. Adolescents with insomnia symptoms, particularly girls, may benefit from interventions to improve negative cognition, mood, and stress, and behavioral strategies to counteract sleep-related maladaptive behaviors.

Indexed as

Sleep Initiation and Maintenance DisordersAdolescentCognitionFemaleHumansMalePsychopathologySleepSleep HygieneAdolescenceDepressionInsomniaNetwork analysisPersonalityStress

Identifiers

PMID35398628
PMCPMC9058217
OpenAlexW4220809540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.