Evidence map›Paper›PMID 35398550›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

Safety of direct oral challenge to amoxicillin in pregnant patients at a Canadian tertiary hospital.

Raymond Mak, Bei Yuan Zhang, Vanessa Paquette, Stephanie C Erdle, Julie E Van Schalkwyk, Tiffany Wong, Melissa Watt, Chelsea Elwood

Abstract readComment
PubMed Publisher
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Validity of PEN-FAST as a clinical decision tool in pregnant patients.The journal of allergy and clinical immunology. Global · 2026
    Article
  4. Review
  5. Obstetric penicillin allergy evaluations.The journal of allergy and clinical immunology. Global · 2025
    Article
  6. Drug allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
  7. Developing and disseminating an electronic penicillin allergy de-labelling tool using the model for improvement framework.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Article
  8. Article
  9. Reliability and validation of an electronic penicillin allergy risk-assessment tool in a pregnant population.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Article
  10. Article
  11. Review
  12. How to Define and Manage Low-Risk Drug Allergy Labels.The journal of allergy and clinical immunology. In practice · 2024
    Review
  13. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  14. Penicillin allergy delabeling: Opportunities for implementation and dissemination.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Review
  15. Penicillin allergy delabelling in pregnancy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  16. Management of the Pregnant Patient with Beta-Lactam Allergy.Current allergy and asthma reports · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Raymond MakDivision of Allergy and Immunology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Division of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada. Electronic address: raymondtmak@yahoo.com.
Bei Yuan ZhangDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada; Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Vanessa PaquetteDepartment of Pharmacy, Children's and Women's Health Centre of British Columbia, Vancouver, BC, Canada.
Stephanie C ErdleDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Julie E Van SchalkwykDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada; Women's Health Research Institute, BC Women's Hospital and Health Centre, Vancouver, BC, Canada.
Tiffany WongDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Melissa WattWomen's Health Research Institute, BC Women's Hospital and Health Centre, Vancouver, BC, Canada.
Chelsea ElwoodDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada; Women's Health Research Institute, BC Women's Hospital and Health Centre, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmoxicillinPenicillinsAdministration, OralAnti-Bacterial AgentsCanadaFemaleHumansPregnancySkin TestsTertiary Care CentersAmoxicillinAnti-Bacterial AgentsPenicillins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.