Evidence map›Paper›PMID 35398005›Full record

ReviewHeart, lung & circulation2022

Myocarditis and Cardiac Complications Associated With COVID-19 and mRNA Vaccination: A Pragmatic Narrative Review to Guide Clinical Practice.

David J Holland, Penni L Blazak, Joshua Martin, Jennifer Broom, Rohan S Poulter, Tony Stanton

Open access · greenAbstract readReview
In one paragraph

Review in Heart, lung & circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Artificial Intelligence in Cardiovascular Health: Insights into Post-COVID Public Health Challenges.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David J HollandCardiology Department, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia; School of Medicine, Griffith University, Sunshine Coast, Qld, Australia; School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Australia. Electronic address: d.holland@uq.edu.au.
Penni L BlazakCardiology Department, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia.
Joshua MartinCardiology Department, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia.
Jennifer BroomSchool of Medicine, The University of Queensland, Brisbane, Qld, Australia; Infectious Diseases Service, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia.
Rohan S PoulterCardiology Department, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia.
Tony StantonCardiology Department, Sunshine Coast University Hospital, Sunshine Coast, Qld, Australia; School of Medicine, Griffith University, Sunshine Coast, Qld, Australia; School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, Qld, Australia.
Sunshine Coast University Hospital · AUGriffith University · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus is likely to remain endemic globally despite widespread vaccination. There is increasing concern for myocardial involvement and ensuing cardiac complications due to COVID-19, however, the available evidence suggests these risks are low. Pandemic publishing has resulted in rapid manuscript availability though pre-print servers. Subsequent article retractions, a lack of standardised definitions, over-reliance on isolated troponin elevation and the heterogeneity of studied patient groups (i.e. severe vs. symptomatic vs all infections) resulted in early concern for high rates of myocarditis in patients with and recovering from COVID-19. The estimated incidence of myocarditis in COVID-19 infection is 11 cases per 100,000 infections compared with an estimated 2.7 cases per 100,000 persons following mRNA vaccination. For substantiated cases, the clinical course of myocarditis related to COVID-19 or mRNA vaccination appears mild and self-limiting, with reports of severe/fulminant myocarditis being rare. There is limited data available on the management of myocarditis in these settings. Clinical guidance for appropriate use of cardiac investigations and monitoring in COVID-19 is needed for effective risk stratification and efficient use of cardiac resources in Australia. An amalgamation of national and international position statements and guidelines is helpful for guiding clinical practice. This paper reviews the current available evidence and guidelines and provides a summary of the risks and potential use of cardiac investigations and monitoring for patients with COVID-19.

Indexed as

COVID-19Heart DiseasesMyocarditisHumansRNA, MessengerSARS-CoV-2VaccinationRNA, MessengerBiomarkerCardiac magnetic resonance imagingCoronavirusCOVID-19EchocardiographymRNAMyocarditisPericarditisSARS-CoV-2TroponinVaccination

Identifiers

PMID35398005
PMCPMC8984702
OpenAlexW4223591645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.