Evidence map›Paper›PMID 35397953›Full record

ArticleSurgery2022

Heath status, frailty, and multimorbidity in patients with emergency general surgery conditions.

Vanessa P Ho, Wyatt P Bensken, Heena P Santry, Christopher W Towe, David F Warner, Alfred F Connors, Siran M Koroukian

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vanessa P HoDepartment of Surgery, MetroHealth Medical Center, Cleveland, OH; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH. Electronic address: vho@metrohealth.org.
Wyatt P BenskenDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH. Electronic address: https://twitter.com/Wyatt_Bensken.
Heena P SantryDepartment of Surgery, Kettering Health, Kettering, OH; NBBJ Design, Columbus, OH. Electronic address: https://twitter.com/heenastat.
Christopher W ToweDepartment of Surgery, University Hospitals Cleveland Medical Center, OH.
David F WarnerDepartment of Sociology, University of Alabama at Birmingham, AL; Center for Family and Demographic Research, Bowling Green State University, OH. Electronic address: https://twitter.com/dwarnersoc.
Alfred F ConnorsDepartment of Medicine, MetroHealth Medical Center, Cleveland, OH.
Siran M KoroukianDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH. Electronic address: https://twitter.com/KoroukianLab.
Case Western Reserve University · USMetroHealth · USUniversity Hospitals of Cleveland · USUniversity of Alabama at Birmingham · US

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
Institutional Career Development CoreKL2TR002547 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI DWEIK, RAED A. · 2018 to 2022
$7.7M
Multi-Level Interventions to Reduce Caries Disparities in Primary Care SettingsUH3DE025487 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI NELSON, SUCHITRA S. · 2017 to 2021
$5.6M
Research Development CoreR24HD050959 · NICHD · BOWLING GREEN STATE UNIVERSITY · PI MANNING, WENDY D. · 2005 to 2016
$2.6M
Computing and Data CoreP2CHD050959 · NICHD · BOWLING GREEN STATE UNIVERSITY · PI BROWN, SUSAN L. · 2016 to 2021
$1.2M
Identifying Electronic Phenotypes associated with Patient Health Outcomes of Interhospital Transfer PatientsR15NR017792 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI REIMER, ANDREW PAUL · 2018 to 2018
$477k
NCATS NIH HHS KL2 TR002547NCI NIH HHS P30 CA043703NICHD NIH HHS P2C HD050959NICHD NIH HHS R24 HD050959NIDCR NIH HHS UH3 DE025487NINR NIH HHS R15 NR017792
6 · The paper itself

Abstract

backgroundAlthough nearly 1 million older adults are admitted for emergency general surgery conditions yearly, the extent to which baseline health influences the development and treatment of emergency general surgery conditions is unknown. We evaluated baseline health and older patients with and without emergency general surgery conditions.

methodsWe used the prospectively collected Medicare Current Beneficiary Survey with Medicare claims and 2 validated health frameworks: (1) Deficit Accumulation Frailty Score and (2) Complex Multimorbidity. Self-reported health and function items were used to derive pre-emergency general surgery conditions Deficit Accumulation Frailty Score and Complex Multimorbidity scores. Deficit Accumulation Frailty Score ranges from 0 (no frailty deficits) to 100 (all possible deficits present). Complex Multimorbidity is a 3-point categorical rank based on the presence of chronic conditions, functional limitations, and geriatric syndromes. Specific survey factors were also examined to determine association with development of emergency general surgery conditions or use of operative management.

resultsOf 54,417 individuals, 1,960 had emergency general surgery conditions (median age 79 [interquartile range 73-84]). Patients with emergency general surgery conditions had significantly higher Deficit Accumulation Frailty Score (19 [interquartile range 11-31] vs 14 [8-24]) and were more likely to be in the most severe Complex Multimorbidity category (38% vs 29%). Emergency general surgery conditions patients had higher proportions of nearly every health category, with the most striking differences in functional limitations. Patients who were treated nonoperatively had the poorest overall baseline health.

conclusionPatients who developed emergency general surgery conditions had more severe health burden than patients who did not, particularly in functional status. Clinicians must better understand the interaction between baseline health vulnerability and emergency surgical disease to improve prognostication and ensure alignment of patient goals and treatment strategies.

Indexed as

FrailtyAgedFrail ElderlyGeriatric AssessmentHumansMedicareMultimorbidityUnited States

Identifiers

PMID35397953
PMCPMC9232899
OpenAlexW4223470323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.