ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2022
Comparative effectiveness of gastric bypass and sleeve gastrectomy on predicted 10-year risk of cardiovascular disease 5 years after surgery.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Risk of Incident Cardiovascular Events Following Roux-en-Y Gastric Bypass Versus Sleeve Gastrectomy: A Claims-based Retrospective Cohort Study.Annals of surgery · 2026Article
- Treatment Decision-making and Weight Loss Expectations for Current Obesity Treatment.Current obesity reports · 2026Review
- Comparative Effectiveness of Sleeve Gastrectomy and One-Anastomosis Gastric Bypass on Cardiovascular Disease Risk: Insights from a Prospective Cohort Study.Obesity surgery · 2026Article
- Adult obesity treatment and prevention: A trans-agency commentary on the research landscape, gaps, and future opportunities.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Review
- Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents.Obesity (Silver Spring, Md.) · 2024Article
- Cardiometabolic Improvements After Metabolic Surgery and Related Presurgery Factors.Journal of the Endocrine Society · 2024Article
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Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundComparative evidence is needed when deciding which bariatric operation to undergo for long-term cardiovascular risk reduction.
objectivesThe Effectiveness of Gastric Bypass vs. Gastric Sleeve for Cardiovascular Disease (ENGAGE CVD) study compared the effectiveness of vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) operations for reduction of the American College of Cardiology and the American Heart Association-predicted 10-year atherosclerotic cardiovascular disease (ASCVD) risk 5 years after surgery.
settingData for this study came from a large integrated healthcare system in the Southern California region of the United States. This is one of the most ethnically diverse (64% non-White) bariatric populations in the literature.
methodsThe ENGAGE CVD cohort consisted of 22,095 patients who underwent VSG or RYGB from 2009-2016. The VSG and RYGB were compared using a local instrumental variable approach to address observed and unobserved confounding, as well as to conduct heterogeneity of treatment effects for patients of different age groups, baseline-predicted 10-year CVD risk using the ASCVD risk score, and those who had type 2 diabetes (T2D) at the time of surgery.
resultsPatients (2771 RYGB and 6256 VVSG) were primarily women (80.6%), Hispanic or non-Hispanic Black (63.7%), and 46 ± 10 years of age, with a body mass index of 43.40 ± 6.5 kg/m
conclusionPredicted 10-year ASCVD risk was low in this population and remained low up to 5 years for those with diabetes, Black and Hispanic patients, and older adults. Literature reporting significant differences between VSG and RYGB in 10-year ASCVD risk may be a result of residual confounding.
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