Evidence map›Paper›PMID 35397526›Full record

ArticleCardiovascular diabetology2022

Liraglutide preserves CD34

Annalisa Sforza, Vera Vigorelli, Erica Rurali, Gianluca Lorenzo Perrucci, Elisa Gambini, Martina Arici, Alessia Metallo, Raffaella Rinaldi, Paolo Fiorina, Andrea Barbuti and 6 more

Open access · goldFull text read
In one paragraph

Article in Cardiovascular diabetology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Extracellular Vesicles Derived from HDrug design, development and therapy · 2024
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Annalisa Sforza *Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Vera Vigorelli *Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Erica RuraliUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Gianluca Lorenzo PerrucciUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Elisa GambiniUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Martina AriciDepartment of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Milan, Italy.
Alessia MetalloDepartment of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Milan, Italy.
Raffaella RinaldiUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Paolo FiorinaDivision of Endocrinology, ASST Fatebenefratelli-Sacco, Milan, Italy.
Andrea BarbutiDepartment of Biosciences, Università degli Studi di Milano, Milan, Italy.
Angela RaucciUnit of Experimental Cardio-Oncology and Cardiovascular Aging, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Elena SaccoDepartment of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Milan, Italy.
Marcella RocchettiDepartment of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Milan, Italy.
Giulio PompilioUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Stefano Genovese *Diabetes, Endocrine and Metabolic Diseases Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Maria Cristina Vinci *Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy. cristina.vinci@ccfm.it.
Centro Cardiologico Monzino · ITUniversity of Milano-Bicocca · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Milan · ITHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlucagon like peptide-1 receptor agonists (GLP-1RAs) have shown to reduce mortality and cardiovascular events in patients with type 2 diabetes mellitus (T2DM). Since the impairment in number and function of vasculotrophic circulating CD34

methodsIn cord blood (CB)-derived CD34

resultsCD34

conclusionWe provided the first evidence that CD34

Indexed as

Diabetes Mellitus, Type 2LiraglutideChemokine CXCL12Glucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsGlucoseHumansHypoglycemic AgentsProto-Oncogene Proteins c-aktStem CellsChemokine CXCL12Glucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsGlucoseHypoglycemic AgentsLiraglutideProto-Oncogene Proteins c-aktCardiovascular diseaseCD34+ hematopoietic stem progenitor cellsGLP-1 receptor agonistType 2 diabetes mellitus

Identifiers

PMID35397526
PMCPMC8994898
OpenAlexW4225669928

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.