Evidence map›Paper›PMID 35397259›Full record

ArticlePsychoneuroendocrinology2022

Association of subjective social status with epigenetic aging among Black and White women.

Elissa J Hamlat, Nancy E Adler, Barbara Laraia, Agus Surachman, Ake T Lu, Joshua Zhang, Steve Horvath, Elissa S Epel

Erratum issuedAbstract read
In one paragraph

Article in Psychoneuroendocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Subjective social standing and lower urinary tract symptoms among Black and White women and men in four regions of the United States.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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  4. Maternal childhood adversity accelerates epigenetic aging of children.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Elissa J HamlatDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, USA. Electronic address: Elissa.Hamlat@ucsf.edu.
Nancy E AdlerDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, USA.
Barbara LaraiaSchool of Public Health, University of California, Berkeley, USA.
Agus SurachmanDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, USA.
Ake T LuDepartment of Human Genetics, University of California, Los Angeles, USA.
Joshua ZhangDepartment of Human Genetics, University of California, Los Angeles, USA.
Steve HorvathDepartment of Human Genetics, University of California, Los Angeles, USA; Department of Biostatistics, University of California, Los Angeles, USA.
Elissa S EpelDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, USA.

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAISSE, CHRISTIAN · 2003 to 2019
$21.8M
Stress, diet quality, and biological aging across the lifespanR24AG048024 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S., MENDES, WENDY BERRY · 2014 to 2025
$6.2M
Psychology & Medicine: Translational Research on Stress, Behavior and DiseaseT32MH019391 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ADLER, NANCY E, EPEL, ELISSA S. · 1991 to 2022
$4.4M
Race, Stress and Dysregulated Eating: Maternal to Child Transmission of ObesityR01HD073568 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI EPEL, ELISSA S., LARAIA, BARBARA A · 2014 to 2018
$2.6M
Early Life Adversity, Cumulative Life Stress, Race, and Cellular Aging in Midlife Women and OffspringR01AG059677 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S., LARAIA, BARBARA A · 2019 to 2021
$1.7M
NIA NIH HHS R01 AG059677NIA NIH HHS R24 AG048024NICHD NIH HHS R01 HD073568NIDDK NIH HHS P30 DK063720NIMH NIH HHS T32 MH019391
6 · The paper itself

Abstract

objectiveSubjective social status (SSS), an individual's assessment of their own social status in relation to others, is associated with health and mortality independently of objective SES; however, no studies have tested whether SSS influences epigenetic aging. The current study examines if SSS is associated with epigenetic age acceleration in both Black and White women, independently of objective SES measured during both childhood and adulthood.

methodFor 9- and 10-year-old Black and White girls, parental education and annual household income was obtained. At ages 39-42, 361 participants (175 Black, 186 White) reported their current education, household income, and SSS, and provided saliva to assess age acceleration using the GrimAge epigenetic clock. Linear regression estimated the association of SSS with epigenetic age acceleration, controlling for objective SES (current education, current income, parents' education, income during childhood), smoking, and counts of cell types.

resultsWhen all objective SES variables were included in the model, SSS remained significantly associated with epigenetic age acceleration, b = - 0.31, p = .003, ß = - 0.15. Black women had significantly greater age acceleration than White women, (t(359) = 5.20, p > .001, d = 0.55) but race did not moderate the association between SSS and epigenetic age acceleration.

conclusionsWomen who rated themselves lower in SSS had greater epigenetic age acceleration, regardless of income and education. There was no difference by race for this association.

Indexed as

Social ClassSocial StatusAdultAgingBlack PeopleChildEpigenesis, GeneticFemaleHumansEpigenetic age accelerationEpigenetic clockRaceSocioeconomic statusSubjective social status

Identifiers

PMID35397259
PMCPMC10228718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.