Evidence map›Paper›PMID 35397015›Full record

ArticleMikrochimica acta2022

Electrochemical immuno determination of connective tissue growth factor levels on nitrogen-doped graphene.

Jing Ma, Junhui Chen, YuanYuan Li, Xinru Zhang-Peng, Hong Wei, Wen Li, Fangdi Hu, Yan Zhang

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jing Ma *School of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China.
Junhui Chen *Department of Pediatrics, Gansu Province People's Hospital, 204 Donggang West Road, Lanzhou, 730000, People's Republic of China.
YuanYuan LiSchool of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China.
Xinru Zhang-PengSchool of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China.
Hong WeiSchool of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China.
Wen LiSchool of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China.
Fangdi HuSchool of Pharmacy@the State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University, Lanzhou, 730000, China. hufd@lzu.edu.cn.
Yan ZhangNational Engineering Research Center for Gelatin-Based Traditional Chinese Medicine, Dong-E-E-Jiao Co., Ltd, Liaocheng, China. zhangyan3261967@126.com.
Lanzhou University · CNGansu Provincial Hospital · CN

Funding

Key Research and Development Project of GanSu Province 20YF2FA019National Key Research and Development Program of China 2018YFC1706300National Key Research and Development Program of China 2018YFC17063003National Natural Science Foundation of China 81972018People's Livelihood Special Project from Technical Innovation Guide Plan of Gansu Province 20CX4FK014Talent Innovation and Entrepreneurship Project of Lanzhou 2020-RC-41Talent Innovation and Entrepreneurship Project of Lanzhou 217-RC115
6 · The paper itself

Abstract

Connective tissue growth factor (CTGF) is a disease marker of rheumatoid arthritis (RA), and its rapid and sensitive detection is essential for the diagnosis of RA. In this work, a three-dimensional pore structure of alkali-activated nitrogen-doped graphene (aN-G) was used as an electrode modification material, and a label-free electrochemical immunosensor for the sensitive detection of CTGF was successfully constructed by the formation of an amide bond between amino groups in protein and carboxyl groups on the carbon surface. Under optimized conditions, the sensor achieved accurate detection of CTGF in the wide range of 0.0625 ~ 2000 pg mL

Indexed as

Arthritis, RheumatoidBiosensing TechniquesConnective Tissue Growth FactorGraphiteHumansImmunoassayNitrogenConnective Tissue Growth FactorGraphiteNitrogenAlkali-activated nitrogen-doped grapheneConnective tissue growth factorDisease classificationElectrochemical immunosensorRheumatoid arthritis

Identifiers

PMID35397015
OpenAlexW4223533954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.