Trial reportEuropean journal of applied physiology2022
Caffeine alters the breathing pattern during high-intensity whole-body exercise in healthy men.
Trial report in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Caffeine intake reverses the impairment of sleep restriction on high-intensity exercise performance.European journal of applied physiology · 2026Trial
- Dose-response effects of caffeine during repeated cycling sprints in normobaric hypoxia to exhaustion.European journal of applied physiology · 2025Trial
- Article
- Effects of Different Doses of Caffeine on Endurance Exercise Performance in the Heat.Life (Basel, Switzerland) · 2025Article
- Women Veterans' Stroke Risk Factors: Identified Prevention Methods and Knowledge Gaps.Military medicine · 2025Article
- Self-Reported Gastrointestinal Symptoms Associated with NSAIDs and Caffeine Consumption in a Jordanian Subpopulation.Medicina (Kaunas, Lithuania) · 2024Article
- The molecular athlete: exercise physiology from mechanisms to medals.Physiological reviews · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe current study investigated the effect of caffeine on the breathing pattern during a high-intensity whole-body exercise.
methodsUsing a randomized, crossover, counterbalanced, and double-blind design, twelve healthy men ingested either 5 mg.kg
resultsCaffeine ingestion increased time to task failure in relation to the placebo (368.1 ± 49.6 s vs. 328.5 ± 56.6 s, p = 0.005). Caffeine also increased tidal volume and inspiratory time throughout the exercise (p < 0.05). Compared to task failure with placebo, task failure with caffeine intake was marked by higher (p < 0.05) minute ventilation (134.8 ± 16.4 vs. 147.6 ± 18.2 L.min
conclusionIn conclusion, ingestion of caffeine alters the breathing pattern by increasing tidal volume and lengthening the inspiratory phase of the respiratory cycle. These findings suggest that caffeine affects the ventilatory system, which may account, in part, for its ergogenic effects during high-intensity whole-body exercises.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.