Evidence map›Paper›PMID 35396951›Full record

ArticlePediatric surgery international2022

Protocolized management of pediatric complicated appendicitis leads to improved outcomes.

Armando Salim Munoz-Abraham, Hector Osei, Sakina Kazmi, Rachelle Damle, Mark S Zemela, Faidah Badru, Mitchell Gibbons, Madelynn Winkelmann, Kaveer Chatoorgoon, Colleen Fitzpatrick and 2 more

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Armando Salim Munoz-AbrahamSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA. salimmunoz@gmail.com.ORCID http://orcid.org/0000-0002-1168-6867
Hector OseiSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Sakina KazmiSaint Louis University School of Medicine, 1465 S Grand Blvd, St. Louis, MO, 63104, USA.
Rachelle DamleSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Mark S ZemelaSaint Louis University School of Medicine, 1465 S Grand Blvd, St. Louis, MO, 63104, USA.
Faidah BadruSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Mitchell GibbonsSaint Louis University School of Medicine, 1465 S Grand Blvd, St. Louis, MO, 63104, USA.
Madelynn WinkelmannSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Kaveer ChatoorgoonSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Colleen FitzpatrickSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Jose GreensponSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Gustavo A VillalonaSection of Pediatric Surgery, Saint Louis University/Cardinal Glennon Children's Medical Center, St. Louis, MO, USA.
Cardinal Glennon Children’s Medical Center · USSaint Louis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate a complicated appendicitis clinical practice guideline at our institution.

methodsRecords were compared before and after protocol implementation. We standardized an ED consult pathway, antibiotic use and need for early appendectomy (EA) versus interval appendectomy (IA). We evaluated demographics, clinical characteristics, and outcomes. Subgroup analysis was performed to compare patients with small abscess treated with IA pre-protocol versus similar patients treated by EA post-protocol.

resultsIn total 246 patients were reviewed (Pre-protocol = 152, Post-protocol = 94). Pre-protocol early appendectomy rate was 51% versus 82% on post-protocol patients. There were no differences in demographics. Post-protocol the use of preoperative imaging significantly decreased (Pre 92% vs. 56%, p = 0.0001), as well as the use of discharge antibiotics (Pre 93% vs. Post 27%, p = 0.0001) with no change in abscess rate. Overall, post-protocol patients had fewer total CT scans performed (Pre 40% vs. Post 28%, p = 0.03) and decreased total length of stay (Pre 7.7 vs. Post 6.5 days, p = 0.049). On subgroup analysis, post-protocol EA with no or small abscess had lower median number of admissions, decreased total LOS (Pre IA 9 days vs. Post EA 5 days, p = 0.00001) and fewer complications (Pre IA 42% vs. EA 22%, p = 0.022).

conclusionThe establishment of a standardized pediatric complicated appendicitis protocol may lead to improved outcomes and resource utilization. Patients presenting with no or small abscess may be the least likely to benefit from interval appendectomy. LEVEL OF EVIDENCE: Level III.

Indexed as

AppendicitisAbscessAnti-Bacterial AgentsAppendectomyChildHumansLength of StayRetrospective StudiesAnti-Bacterial AgentsAbscessAppendicitisEarly appendectomyInterval appendectomyOutcomes

Identifiers

PMID35396951
OpenAlexW4223613436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.