Evidence map›Paper›PMID 35396708›Full record

ArticleJournal of anatomy2022

Differential immunostaining patterns of transient receptor potential (TRP) ion channels in the rat nodose ganglion.

Safdar Jawaid, Amanda I Herring, Paulina M Getsy, Stephen J Lewis, Michiko Watanabe, Hana Kolesova

Open access · bronzeAbstract read
In one paragraph

Article in Journal of anatomy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. The therapeutic pipeline in migraine: What does the future hold?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  2. Review
  3. Review
  4. Hypoxia augments TRPM3-mediated calcium influx in vagal sensory neurons.Autonomic neuroscience : basic & clinical · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Safdar JawaidDivisions of Pediatric Cardiology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Amanda I HerringDivisions of Pediatric Cardiology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Paulina M GetsyPediatric Pulmonology, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Stephen J LewisPediatric Pulmonology, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Michiko WatanabeDivisions of Pediatric Cardiology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0002-6295-6759
Hana KolesovaDepartment of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID 0000-0003-1861-9445
University School · USCharles University · CZ

Funding

Case Western Reserve UniversityCzech Academy of SciencesCzech Science FoundationFulbright Scholarship from the Fulbright Commission (HK)
6 · The paper itself

Abstract

Vagal afferents regulate numerous physiological functions including arterial blood pressure, heart rate, breathing, and nociception. Cell bodies of vagal afferents reside in the inferior vagal (nodose) ganglia and their stimulation by various means is being considered as a way to regulate cardiorespiratory responses and control pain sensations. Stimulation of the nodose by exposure to infrared light is recently being considered as a precise way to elicit responses. These responses would likely involve the activity of temperature-sensitive membrane-bound channels. While papers have been published to track the expression of these transient receptor potential ion channels (TRPs), further studies are warranted to determine the in situ expression of the endogenous TRP proteins in the nodose ganglia to fully understand their pattern of expression, subcellular locations, and functions in this animal model. TRP ion channels are a superfamily of Na

Indexed as

Transient Receptor Potential ChannelsTRPM Cation ChannelsAnimalsMaleNodose GanglionRatsRats, Sprague-DawleyTRPV Cation ChannelsVagus NerveTransient Receptor Potential ChannelsTRPM3 protein, ratTRPM Cation ChannelsTrpv4 protein, ratTRPV Cation Channelsautonomic nervous systemblood vesselsconfocal microscopyimmunohistochemistrynodose ganglionTRPA1TRPC1TRPM3TRPM8TRPV1TRPV4vagus nerve

Identifiers

PMID35396708
PMCPMC9296033
OpenAlexW4223450006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.