Evidence map›Paper›PMID 35396698›Full record

ArticleAging clinical and experimental research2022

Prevalence and features of delirium in older patients admitted to rehabilitation facilities: a multicenter study.

Chiara Sidoli, Antonella Zambon, Elena Tassistro, Emanuela Rossi, Enrico Mossello, Marco Inzitari, Antonio Cherubini, Alessandra Marengoni, Alessandro Morandi, Giuseppe Bellelli and 1 more

Open access · bronzeAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Chiara SidoliSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Antonella ZambonUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milano, Italy.
Elena TassistroBicocca Center of Bioinformatics, Biostatistics and Bioimaging (B4 Center), School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Emanuela RossiBicocca Center of Bioinformatics, Biostatistics and Bioimaging (B4 Center), School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Enrico MosselloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Marco InzitariIntermediate Care, Research and Teaching, Parc Sanitari Pere Virgili, Barcelona, Spain.
Antonio CherubiniGeriatria, Accettazione Geriatrica e Centro di Ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.
Alessandra MarengoniDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Alessandro Morandi *Department of Rehabilitation, Azienda Speciale di Cremona Solidale, A.S.C.S., Cremona, Italy. morandi.alessandro@gmail.com.ORCID http://orcid.org/0000-0003-4848-2507
Giuseppe Bellelli *School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
on behalf of the Italian Study Group on Delirium
Azienda Ospedaliera San Gerardo · ITVall d'Hebron Institut de Recerca · ESIstituti di Ricovero e Cura a Carattere Scientifico · ITIRCCS Istituto Auxologico Italiano · ITUniversity of Milano-Bicocca · ITUniversity of Brescia · ITAzienda Ospedaliero-Universitaria Careggi · ITParque Sanitario Pere Virgili · ESAllen Institute for Brain Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelirium is thought to be common across various settings of care; however, still little research has been conducted in rehabilitation.

aimWe investigated the prevalence of delirium, its features and motor subtypes in older patients admitted to rehabilitation facilities during the three editions of the "Delirium Day project".

methodsWe conducted a cross-sectional study in which 1237 older patients (age ≥ 65 years old) admitted to 50 Italian rehabilitation wards during the three editions of the "Delirium Day project" (2015 to 2017) were included. Delirium was evaluated through the 4AT and its motor subtype with the Delirium Motor Subtype Scale.

resultsDelirium was detected in 226 patients (18%), and the most recurrent motor subtype was mixed (37%), followed by hypoactive (26%), hyperactive (21%) and non-motor one (16%). In a multivariate Poisson regression model with robust variance, factors associated with delirium were: disability in basic (PR 1.48, 95%CI: 1.17-1.9, p value 0.001) and instrumental activities of daily living (PR 1.58, 95%CI: 1.08-2.32, p value 0.018), dementia (PR 2.10, 95%CI: 1.62-2.73, p value < 0.0001), typical antipsychotics (PR 1.47, 95%CI: 1.10-1.95, p value 0.008), antidepressants other than selective serotonin reuptake inhibitors (PR 1.3, 95%CI: 1.02-1.66, p value 0.035), and physical restraints (PR 2.37, 95%CI: 1.68-3.36, p value < 0.0001).

conclusionThis multicenter study reports that 2 out 10 patients admitted to rehabilitations had delirium on the index day. Mixed delirium was the most prevalent subtype. Delirium was associated with unmodifiable (dementia, disability) and modifiable (physical restraints, medications) factors. Identification of these factors should prompt specific interventions aimed to prevent or mitigate delirium.

Indexed as

DeliriumDementiaActivities of Daily LivingAgedCross-Sectional StudiesHumansPrevalenceDeliriumDementiaDisabilityPhysical restraintRehabilitation

Identifiers

PMID35396698
OpenAlexW4223476048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.