Evidence map›Paper›PMID 35396532›Full record

ArticleScientific reports2022

A fully water coupled oblique light-sheet microscope.

Yiyang Gong, Yuqi Tian, Casey Baker

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Recent advances in oblique plane microscopy.Nanophotonics (Berlin, Germany) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yiyang GongDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA. yiyang.gong@duke.edu.
Yuqi TianDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Casey BakerDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Duke University · US

Funding

Large-scale cellular-resolution voltage imaging of the zebrafish brainUF1NS107678 · NINDS · DUKE UNIVERSITY · PI GONG, YIYANG · 2018 to 2018
$1.2M
NINDS NIH HHS 1UF1NS107678NINDS NIH HHS UF1 NS107678
6 · The paper itself

Abstract

Recently developed descanned versions of the oblique light-sheet microscope promise to enable high-frame rate volumetric imaging in a variety of convenient preparations. The efficiency of these microscopes depends on the implementation of the objective coupling that turns the intermediate imaging plane. In this work, we developed a fully immersed coupling strategy between the middle and end objectives of the oblique light-sheet microscope to enable facile alignment and high efficiency coupling. Our design outperformed conventional designs that used only air objectives in resolution and light-collection power. We further demonstrated our design's ability to capture large fields-of-view when paired with a camera with built-in electronic binning. We simultaneously imaged the forebrain and hindbrain of larval zebrafish and found clusters of activity localized to each region of the brain.

Indexed as

WaterZebrafishAnimalsBrainLarvaMicroscopyWater

Identifiers

PMID35396532
PMCPMC8993908
OpenAlexW4223442426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.