Evidence map›Paper›PMID 35396471›Full record

ArticleNature methods2022

Unlocking capacities of genomics for the COVID-19 response and future pandemics.

Sergey Knyazev, Karishma Chhugani, Varuni Sarwal, Ram Ayyala, Harman Singh, Smruthi Karthikeyan, Dhrithi Deshpande, Pelin Icer Baykal, Zoia Comarova, Angela Lu and 25 more

Abstract read
In one paragraph

Article in Nature methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. The Era of Large-Scale Data in Biological Sciences.Advances in experimental medicine and biology · 2026
    Review
  6. The value of large-scale programmes in human genomics.European journal of human genetics : EJHG · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Sergey Knyazev *Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-0385-1831
Karishma Chhugani *Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-8764-9352
Varuni SarwalDepartment of Computer Science, University of California Los Angeles, Los Angeles, CA, USA.
Ram AyyalaDepartment of Translational Biomedical Informatics, University of Southern California, Los Angeles, CA, USA.
Harman SinghDepartment of Electrical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi, India.
Smruthi KarthikeyanDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Dhrithi DeshpandeDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.
Pelin Icer BaykalDepartment of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Zoia ComarovaAstani Department of Civil and Environmental Engineering, University of Southern California, Los Angeles, CA, USA.
Angela LuDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.
Yuri PorozovWorld-Class Research Center "Digital biodesign and personalized healthcare", I.M. Sechenov First Moscow State Medical University, Moscow, Russia.ORCID http://orcid.org/0000-0002-5450-3135
Tetyana I VasylyevaDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Joel O WertheimDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Braden T TierneyDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Charles Y ChiuDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-2915-2094
Ren SunDepartment of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, USA.
Aiping WuInstitute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Malak S AbedalthagafiGenomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Victoria M PakEmory University, School of Nursing, Atlanta, GA, CA, USA.
Shivashankar H NagarajCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Adam L SmithAstani Department of Civil and Environmental Engineering, University of Southern California, Los Angeles, CA, USA.
Pavel SkumsDepartment of Computer Science, College of Art and Science, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-4007-5624
Bogdan PasaniucDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Andrey KomissarovSmorodintsev Research Institute of Influenza, Saint Petersburg, Russia.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-1850-1642
Eric BortzDepartment of Biological Sciences, University of Alaska Anchorage, Anchorage, AK, CA, USA.ORCID http://orcid.org/0000-0002-1376-0012
Philippe LemeyDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven-University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2826-5353
Fyodor KondrashovInstitute of Science and Technology Austria, Klosterneuburg, Austria.
Niko BeerenwinkelDepartment of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.ORCID http://orcid.org/0000-0002-0573-6119
Tommy Tsan-Yuk LamState Key Laboratory of Emerging Infectious Diseases, School of Public Health, The University of Hong Kong, Hong Kong SAR, P.R. China.
Nicholas C WuDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Alex ZelikovskyDepartment of Computer Science, College of Art and Science, Georgia State University, Atlanta, GA, USA.
Rob KnightDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-0975-9019
Keith A CrandallComputational Biology Institute and Department of Biostatistics & Bioinformatics, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.ORCID http://orcid.org/0000-0002-0836-3389
Serghei MangulDepartment of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, CA, USA. serghei.mangul@gmail.com.ORCID http://orcid.org/0000-0003-4770-3443

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI STACY M. RASMUS · 2012 to 2026
$66.1M
Technology CoreU19AI135995 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI Bryan Briney · 2018 to 2026
$32.0M
Joint genomic and statistical analyses of schizophrenia and bipolar to decipher genetic susceptibilityR01MH115676 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Roel A Ophoff, Bogdan Pasaniuc · 2018 to 2026
$5.9M
Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
PRS Center for Admixed Populations (CAPE)U01HG011715 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI Eimear Elizabeth Kenny, Leslie A Lange · 2021 to 2026
$5.2M
Supplement for MINI point-of-use deviceU01DA053941 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI MASON, CHRISTOPHER EDWARD, SCHURER, STEPHAN C · 2021 to 2022
$5.2M
Collaborative multi-site project to speed the identification and management of rare genetic immune diseasesR01AI153827 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUTTE, MANISH J, PASANIUC, BOGDAN · 2021 to 2025
$3.9M
Automation and Evaluation of Real-Time Transmission Network-Based HIV Prevention Services in New York CityR01AI135992 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERTHEIM, JOEL OKRENT · 2018 to 2022
$3.6M
Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantationR01AI151059 · NIAID · CORNELL UNIVERSITY · PI DADHANIA, DARSHANA, DE VLAMINCK, IWIJN · 2020 to 2024
$3.4M
Sequence-function relationship of influenza broadly neutralizing antibodiesR01AI167910 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Nicholas C. Wu · 2022 to 2026
$2.5M
Statistical Innovation to Integrate Sequences and Phenotypes for Scalable Phylodynamic InferenceR01AI153044 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Marc A. Suchard · 2021 to 2026
$2.4M
High-throughput identification of antibody features for sequence-based epitope predictionDP2AT011966 · NCCIH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI WU, NICHOLAS C. · 2021 to 2024
$2.4M
NCCIH NIH HHS DP2 AT011966NCEZID CDC HHS U01 CK000539NCI NIH HHS R21 CA241044NHGRI NIH HHS R01 HG009120NHGRI NIH HHS U01 HG011715NIAID NIH HHS R00 AI139445NIAID NIH HHS R01 AI125416NIAID NIH HHS R01 AI135992NIAID NIH HHS R01 AI151059NIAID NIH HHS R01 AI153044NIAID NIH HHS R01 AI153827NIAID NIH HHS R01 AI167910NIAID NIH HHS R21 AI129851NIAID NIH HHS U19 AI135995NIBIB NIH HHS R01 EB025022NIDA NIH HHS U01 DA053941NIGMS NIH HHS P20 GM103395NIMH NIH HHS R01 MH115676Wellcome TrustWellcome Trust 206298/Z/17/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19PandemicsGenomicsHumansSARS-CoV-2

Identifiers

PMID35396471
PMCPMC9467803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.