Evidence map›Paper›PMID 35396343›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2022

A Review of the Neurobiological Mechanisms that Distinguish Between Loudness Recruitment and Hyperacusis.

Lin Shi, Rui Zhao, Xinxin Li, Wei Sun, Xiuli Liu

Open access · hybridAbstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Auditory pathways in migraine and vestibular migraine: New insights into sound sensitivity and spectral resolution dysfunction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lin ShiDepartment of Otorhinolaryngology, The First Hospital of Dalian Medical University, Dalian, Liaoning, China (mainland).
Rui ZhaoDepartment of Otorhinolaryngology, The First Hospital of Dalian Medical University, Dalian, Liaoning, China (mainland).
Xinxin LiDepartment of Otorhinolaryngology, The First Hospital of Dalian Medical University, Dalian, Liaoning, China (mainland).
Wei SunDepartment of Communicative Disorders and Sciences, Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY, USA.
Xiuli LiuDepartment of Otorhinolaryngology, The First Hospital of Dalian Medical University, Dalian, Liaoning, China (mainland).
First Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CNUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loudness recruitment is a common symptom of hearing loss induced by cochlear lesions, which is defined as an abnormally fast growth of loudness perception of sound intensity. This is different from hyperacusis, which is defined as "abnormal intolerance to regular noises" or "extreme amplification of sounds that are comfortable to the average individual". Although both are characterized by abnormally high sound amplification, the mechanisms of occurrence are distinct. Damage to the outer hair cells alters the nonlinear characteristics of the basilar membrane, resulting in aberrant auditory nerve responses that may be connected to loudness recruitment. In contrast, hyperacusis is an aberrant condition characterized by maladaptation of the central auditory system. Peripheral injury can produce fluctuations in loudness recruitment, but this is not always the source of hyperacusis. Hyperacusis can also be accompanied by aversion to sound and fear of sound stimuli, in which the limbic system may play a critical role. This brief review aims to present the current status of the neurobiological mechanisms that distinguish between loudness recruitment and hyperacusis.

Indexed as

Hearing LossHyperacusisAcoustic StimulationCochlear NerveHumansLoudness Perception

Identifiers

PMID35396343
PMCPMC9006468
OpenAlexW4223584166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.