Evidence map›Paper›PMID 35396333›Full record

ArticleJournal of neurointerventional surgery2023

Evaluation of time-resolved whole brain flat panel detector perfusion imaging using RAPID ANGIO in patients with acute stroke: comparison with CT perfusion imaging.

Christoph C Kurmann, Johannes Kaesmacher, Daniel L Cooke, Marios Psychogios, Johannes Weber, Demetrius K Lopes, Gregory W Albers, Pasquale Mordasini

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05644938 (Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke Trial), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05644938 naunknown statusnot on this map

Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke Trial

TypeinterventionalSponsorCan Tho Stroke International Services HospitalRan2023 to 2023Enrolled50ConditionsAcute Ischemic StrokeArmsStandard workflow, One-stop
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Christoph C KurmannDepartment of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-5770-5675
Johannes KaesmacherDepartment of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-9177-2289
Daniel L CookeDepartment of Radiology and Biomedical Imaging, University California San Francisco, San Francisco, California, USA.
Marios PsychogiosDepartment of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Johannes WeberClinic of Radiology and Nuclear Medicine, Diagnostic and Interventional Neuroradiology, Kantonsspital St Gallen, St. Gallen, Switzerland.
Demetrius K LopesDepartment of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA.
Gregory W AlbersDepartment of Neurology and Neurosurgery, Stanford University, Stanford, California, USA.
Pasquale MordasiniDepartment of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland pasquale.mordasini@insel.ch.
University Hospital of Bern · CHKantonsspital St. Gallen · CHRush University Medical Center · USStanford University · USUniversity Hospital of Basel · CHUniversity of Bern · CHUniversity of California System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn contrast to conventional CT perfusion (CTP) imaging, flat panel detector CT perfusion (FD-CTP) imaging can be acquired directly in the angiosuite.

objectiveTo evaluate time-resolved whole brain FD-CTP imaging and assess clinically important qualitative and quantitative perfusion parameters in correlation with previously acquired conventional CTP using the new RAPID for ANGIO software.

methodsWe included patients with internal carotid artery occlusions and M1 or M2 occlusions from six centers. All patients underwent mechanical thrombectomy (MT) with preinterventional conventional CTP and FD-CTP imaging. Quantitative performance was determined by comparing volumes of infarct core, penumbral tissue, and mismatch. Eligibility for MT according to the perfusion imaging criteria of DEFUSE 3 was determined for each case from both conventional CTP and FD-CTP imaging.

resultsA total of 20 patients were included in the final analysis. Conventional relative cerebral blood flow (rCBF) <30% and FD-CTP rCBF <45% showed good correlation (R

conclusionsIn our multicenter study, time-resolved whole brain FD-CTP was technically feasible, and qualitative and quantitative perfusion results correlated with those obtained with conventional CTP.

Indexed as

Brain IschemiaStrokeBrainHumansPerfusion ImagingRetrospective StudiesThrombectomyTomography, X-Ray ComputedCT perfusionStrokeThrombectomy

Identifiers

PMID35396333
PMCPMC10086455
OpenAlexW4223522360

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.