Evidence map›Paper›PMID 35396330›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Quantitative BONCAT Allows Identification of Newly Synthesized Proteins after Optic Nerve Injury.

Sahil H Shah, Lucio M Schiapparelli, Satoshi Yokota, Yuanhui Ma, Xin Xia, Sahana Shankar, Sarah Saturday, Michael Nahmou, Catalina Sun, John Yates and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
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  7. Activity-Induced Cortical Glutamatergic Neuron Nascent Proteins.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sahil H ShahMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.
Lucio M SchiapparelliNeuroscience Department and Dorris Neuroscience Center, Scripps Research, La Jolla, California 92093.
Satoshi YokotaMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.ORCID https://orcid.org/0000-0002-3727-7279
Yuanhui MaDepartment of Molecular Medicine, Scripps Research, La Jolla, California 92093.
Xin XiaMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.ORCID https://orcid.org/0000-0002-6261-6690
Sahana ShankarMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.
Sarah SaturdayNeuroscience Department and Dorris Neuroscience Center, Scripps Research, La Jolla, California 92093.
Michael NahmouMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.
Catalina SunMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303.
John YatesDepartment of Molecular Medicine, Scripps Research, La Jolla, California 92093.
Hollis T ClineNeuroscience Department and Dorris Neuroscience Center, Scripps Research, La Jolla, California 92093.ORCID https://orcid.org/0000-0002-4887-9603
Jeffrey L GoldbergMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, California 94303 jlgoldberg@stanford.edu.
Vision Eye Institute · AUScripps Health · USScripps Research Institute · USSmith-Kettlewell Eye Research Institute · US

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI YATES III, JOHN R · 2012 to 2021
$20.7M
Activity-dependent Development of Visual System DevelopmentR01EY011261 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 1996 to 2018
$11.1M
Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI TIRIN MOORE · 2017 to 2026
$8.0M
Core Grant for Vision ResearchP30EY019005 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2009 to 2018
$7.7M
Quantitative Proteome Analysis of Brain DevelopmentR01MH067880 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI YATES III, JOHN R · 2003 to 2017
$7.1M
Molecular Discovery for Optic Nerve RegenerationU01EY027261 · NEI · STANFORD UNIVERSITY · PI GOLDBERG, JEFFREY L, HUBERMAN, ANDREW D · 2016 to 2019
$3.0M
Development of midbrain circuitryR01EY027437 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2018 to 2020
$1.9M
Exosome-mediated cell-cell signaling in Rett SyndromeR01MH103134 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T., MUOTRI, ALYSSON R. · 2013 to 2016
$1.4M
NEI NIH HHS P30 EY019005NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY011261NEI NIH HHS R01 EY027437NEI NIH HHS U01 EY027261NIGMS NIH HHS P41 GM103533NIMH NIH HHS R01 MH067880NIMH NIH HHS R01 MH103134
6 · The paper itself

Abstract

Retinal ganglion cells (RGCs) die after optic nerve trauma or in degenerative disease. However, acute changes in protein expression that may regulate RGC response to injury are not fully understood, and detailed methods to quantify new protein synthesis have not been tested. Here, we develop and apply a new

Indexed as

Optic Nerve InjuriesAxonsHumansNerve RegenerationRetinaRetinal Ganglion Cellsneurodegenerationoptic nerveprotein synthesisproteomicsretina

Identifiers

PMID35396330
PMCPMC9097770
OpenAlexW4223537307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.