Evidence map›Paper›PMID 35396240›Full record

ArticleBMJ case reports2022

Acquired haemophilia A associated to autoimmune thyroiditis and pangastritis.

Joana Isabel Marques Dias, Marta Azevedo Ferreira, Ana Grilo, Ana Isabel Reis

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joana Isabel Marques DiasInternal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal joana.marques.dias92@gmail.com.
Marta Azevedo FerreiraInternal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal.
Ana GriloInternal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal.
Ana Isabel ReisInternal Medicine, Hospital Beatriz Angelo, Loures, Lisboa, Portugal.
Hospital Beatriz Ângelo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired haemophilia A is a rare condition defined by the presence of coagulation inhibitors, which are autoantibodies directed against factor VIII that interfere with its activity. We report a case of a 69-year-old woman that presented with knee haemarthrosis followed by spontaneous retroperitoneal haematoma. On coagulation studies, she presented normal prothrombin time with prolonged activated partial thromboplastin time non-correcting on mixture test, low titers of factor VIII and was detected factor VIII inhibitor that led to diagnosis of acquired haemophilia A. She was managed with supportive measures to control haemorrhage and immunosuppressive therapy to eradicate inhibitors, initially with corticosteroids, with partial transitory response, after which she developed new spontaneous haematomas. Rituximab was started at that time, with a good outcome. The additional aetiological study identified autoimmune thyroiditis and autoimmune pangastritis, an association rarely described in literature.

Indexed as

Hashimoto DiseaseHemophilia AThyroiditis, AutoimmuneAgedAutoantibodiesFactor VIIIFemaleHematomaHemorrhageHumansAutoantibodiesFactor VIIIHaematology (incl blood transfusion)ImmunologyThyroiditis

Identifiers

PMID35396240
PMCPMC8995960
OpenAlexW4223626509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.