Evidence map›Paper›PMID 35395486›Full record

ArticleJournal of neuroimmunology2022

Retinal pathology in spontaneous opticospinal experimental autoimmune encephalitis mice.

Jing Jin, Mark Shneyderman, Matthew D Smith, Marjan Gharagozloo, Elias S Sotirchos, Peter A Calabresi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroimmunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jing JinDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: jjin11@jhmi.edu.
Mark ShneydermanDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: mshneyd1@alumni.jh.edu.
Matthew D SmithDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: matthewsmith@jhu.edu.
Marjan GharagozlooDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: mgharag1@jhu.edu.
Elias S SotirchosDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: ess@jhmi.edu.
Peter A CalabresiDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University, Baltimore, MD, United States of America; Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: pcalabr1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

The Role of KV1.3 in Effector T cellsR01NS041435 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI CALABRESI, PETER A · 2000 to 2025
$5.8M
NINDS NIH HHS R01 NS041435
6 · The paper itself

Abstract

Retinal ganglion cells (RGC) are lost as a sequela of optic nerve inflammation in myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD), but the mechanisms of injury remain incompletely understood and there remains a need to characterize the murine model of MOGAD. Several studies have shown that RGC loss occurs in association with optic neuritis in MOG

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalOptic NeuritisRetinaAnimalsEncephalitisHashimoto DiseaseInflammationMiceMice, Inbred C57BLMyelin-Oligodendrocyte GlycoproteinMyelin-Oligodendrocyte GlycoproteinAstrocytesEAEOptic neuritisRetinal ganglion cells

Identifiers

PMID35395486
PMCPMC9106884
OpenAlexW4220743860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.