Evidence map›Paper›PMID 35395419›Full record

ArticleJournal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC2022

Preeclampsia and Severe Maternal Morbidity During the COVID-19 Pandemic: A Population-Based Cohort Study in Ontario, Canada.

John W Snelgrove, Andrea N Simpson, Rinku Sutradhar, Karl Everett, Ning Liu, Nancy N Baxter

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Pre-eclampsia.Nature reviews. Disease primers · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

John W SnelgroveMaternal-Fetal Medicine, Mount Sinai Hospital, Department of Obstetrics & Gynaecology, University of Toronto, Toronto, ON; Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON. Electronic address: John.Snelgrove@Sinaihealth.Ca.
Andrea N SimpsonInstitute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON; Obstetrics & Gynaecology, St. Michael's Hospital/Unity Health Toronto, Department of Obstetrics & Gynaecology, University of Toronto, Toronto, ON; ICES, Toronto, ON; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON.
Rinku SutradharICES, Toronto, ON; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON.
Karl EverettICES, Toronto, ON.
Ning LiuInstitute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON; ICES, Toronto, ON.
Nancy N BaxterInstitute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON; ICES, Toronto, ON; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON; Melbourne School of Population & Global Health, University of Melbourne, Melbourne, VIC, Australia.
Institute for Work & Health · CA3M (United States) · USSt. Michael's Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSignificant changes to the delivery of obstetrical care that occurred with the onset of the COVID-19 pandemic may be associated with higher risks of adverse maternal outcomes. We evaluated preeclampsia/HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome and composite severe maternal morbidity (SMM) among pregnant people who gave birth during the COVID-19 pandemic and compared these data with those of people who gave birth before the pandemic in Ontario, Canada.

methodsThis was a population-based, retrospective cohort study using linked administrative data sets from ICES. Data on pregnant people at ≥20 weeks gestation who gave birth between March 15, 2020, and September 30, 2021, were compared with those of pregnant people who gave birth within the same date range for the years 2015-2019. We used multivariable logistic regression to assess the effect of the pandemic period on the odds of preeclampsia/HELLP syndrome and composite SMM, adjusting for maternal baseline characteristics and comorbidities.

resultsThere were no differences between the study periods in the adjusted odds ratios (aORs) for preeclampsia/HELLP syndrome among primiparous (aOR 1.00; 95% CI 0.91-1.11) and multiparous (aOR 0.94; 95% CI 0.81-1.09) patients and no differences for composite SMM (primiparous, aOR 1.00; 95% CI 0.95-1.05; multiparous, aOR 1.01; 95% CI 0.95-1.08).

conclusionAdverse maternal outcomes were not higher among pregnant people who gave birth during the first 18 months of the COVID-19 pandemic in Ontario, Canada, when compared with those who gave birth before the pandemic.

Indexed as

COVID-19HELLP SyndromePre-EclampsiaCohort StudiesFemaleHumansOntarioPandemicsPregnancyRetrospective Studiescohort studyCOVID-19HELLP syndromeOntariopre-eclampsiapregnancypregnancy complications

Identifiers

PMID35395419
PMCPMC8979839
OpenAlexW4223606159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.