Evidence map›Paper›PMID 35395181›Full record

ArticleCell stem cell2022

c-Maf: The magic wand that turns on LSEC fate.

Anna R Smith, Valerie Gouon-Evans

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Sourcing cells forFrontiers in medical technology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anna R SmithSection of Gastroenterology, Center for Regenerative Medicine (CReM), Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
Valerie Gouon-EvansSection of Gastroenterology, Center for Regenerative Medicine (CReM), Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA. Electronic address: valerige@bu.edu.
Boston Medical Center · USBoston University · US

Funding

A multi-modular approach for human pluripotent stem cell-based liver regenerationR01DK124361 · NIDDK · BOSTON MEDICAL CENTER · PI GOUON-EVANS, VALERIE B · 2020 to 2023
$2.2M
NIDDK NIH HHS R01 DK124361
6 · The paper itself

Abstract

In this issue of Cell Stem Cell, Gómez-Salinero et al. (2022) identify c-Maf as a driver for murine liver sinusoidal endothelial cell (LSEC) fate and function during liver development, homeostasis, and repair. Similarly, c-Maf defines human LSECs, and its overexpression specializes generic HUVECs into functional induced-LSECs, potentiating regenerative therapeutics.

Indexed as

Endothelial CellsLiverProto-Oncogene Proteins c-mafAnimalsHumansMiceMAF protein, humanMaf protein, mouseProto-Oncogene Proteins c-maf

Identifiers

PMID35395181
OpenAlexW4223487329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.