Evidence map›Paper›PMID 35395154›Full record

ArticleJournal of agricultural and food chemistry2022

Bacterial Lipodepsipeptides and Some of Their Derivatives and Cyclic Dipeptides as Potential Agents for Biocontrol of Pathogenic Bacteria and Fungi of Agrarian Plants.

Stefany Castaldi, Alessio Cimmino, Marco Masi, Antonio Evidente

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Effects ofMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Cyclo(l-Pro-l-Tyr) Isolated from the Human Skin CommensalInternational journal of molecular sciences · 2024
    Article
  9. Review
  10. Review
  11. Journal of fungi (Basel, Switzerland) · 2023
    Article
  12. Antibacterial Activity of Two New Cassane Diterpenoids fromInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Bioactive Lipodepsipeptides Produced by Bacteria and Fungi.International journal of molecular sciences · 2022
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefany CastaldiDepartment of Biology, University of Naples Federico II, Complesso Universitario Monte S. Angelo, 80126 Napoli, Italy.
Alessio CimminoDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, 80126 Napoli, Italy.ORCID 0000-0002-1551-4237
Marco MasiDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, 80126 Napoli, Italy.ORCID 0000-0003-0609-8902
Antonio EvidenteDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, 80126 Napoli, Italy.ORCID 0000-0001-9110-1656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biotic stresses (fungi, bacteria, insects, weeds, etc.) are some of the most important causes of the decrease in the quality and quantity of crops that could become an emergency due to a noteworthy increase in the world population. Thus, to overcome these problems, massive use of chemical pesticides has been carried out with heavy consequences for environmental pollution and food safety. An eco-friendly alternative can be using natural compound-based biopesticides with high efficacy and selectivity. Some bacterial lipodepsipeptides (tolaasins I, II, A, D, and E and WLIP together with hexacetyl- and tetrahydro-tolaasin I and WLIP methyl ester) and cyclic dipeptides (cyclo(l-Pro-l-Tyr), cyclo(d-Pro-l-Tyr), cyclo(l-Pro-l-Val), and cyclo(l-Pro-l-Leu)) were assayed against several pathogenic bacteria and fungi of important agrarian plants. Lipodepsipeptides showed strong growth inhibition of all microorganisms tested in the range of 0.1-0.8 μg/mL, while cyclodipeptides, despite preserving this ability, showed a noteworthily reduced antimicrobial activity being active only in the range of 15-900 μg/mL. Among the lipodepsipeptides and cyclic dipeptides assayed, tolaasin d and cyclo(l-Pro-l-Tyr) (also named maculosin-1) appeared to be the most toxic compounds. Some structure-activity relationships of lipodepsipeptides were also discussed along with their practical application as biopesticides in agriculture.

Indexed as

Biological Control AgentsFungiBacteriaDipeptidesMicrobial Sensitivity TestsPeptides, CyclicPlantsBiological Control AgentsDipeptidesPeptides, Cyclicagrarian plant diseasesantimicrobial activitybacterial and fungal pathogensbiopesticidescyclic dipeptideslipodepsipeptides

Identifiers

PMID35395154
PMCPMC9026286

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.