ArticlePloS one2022
Foeto-maternal complications associated with low birth weight: A prospective multicenter study in northern Ghana.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 6 citations in OpenAlex.
- Predictors of low birth weight: a hospital-based matched case-control study in the Ashanti region, Ghana.Global epidemiology · 2026Article
- Coverage and factors associated with receipt of early newborn postnatal care components in Afghanistan: findings from the 2022-2023 multiple indicator cluster survey.Global health action · 2026Article
- Pre-Eclampsia Among Pregnant Women in Ghana: A Systematic Review & Meta-Analysis of the Current Prevalence, Risk Factors, and Perinatal Outcomes.Health science reports · 2026Review
- Do maternal self-reported socio-demographic and green space characteristics influence neonatal birth weight? Evidence from Ghana.Maternal health, neonatology and perinatology · 2026Article
- Could Ultrasonographic Measurements of the Umbilical Cord be a Predictor of Birth Weight? A Health Facility-Based Cross-Sectional Study.Health science reports · 2026Article
- Low Birth Weight and Associated Factors in Sudan: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Predictors of low birth weight deliveries at a primary health care facility: Suhum Government Hospital, Ghana - a retrospective cross-sectional study.BMJ public health · 2026Article
- Low birth weight risk prediction model: a prognostic study in the Birhan field site in Ethiopia.Journal of global health · 2025Article
- Caesarean section delivery and its associated factors in Ghana: A multilevel analysis.PloS one · 2025Article
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study evaluated the socio-demographic characteristics, obstetric variables and foeto-maternal complications associated with low birth weight (LBW) in order to provide better treatment and management options.
methodsThe prospective study conducted from February, 2019 to June, 2020 recruited 312 primigravid pregnant women who reported for antenatal care in three tertiary referral hospitals in northern Ghana. Their socio-demographic, obstetric and adverse foeto-maternal outcome information were obtained with a well-structured questionnaire according to the World Health Organisation (WHO) guidelines. Participants' blood samples were collected for haematological tests. Odds ratio [OR, 95% confidence interval (CI)] for the association between socio-demographic, obstetric characteristics, foeto-maternal complications and haematological tests in relation to LBW were assessed using logistic regression model.
resultsThis study reported a LBW prevalence of 13.5%. Increasing maternal systolic blood pressure (SBP) and diastolic blood pressure (DBP) at 1st visit, before and after delivery significantly increased the odds of LBW. Preterm delivery (PTD<37 weeks) (COR = 9.92, 95% CI (4.87-2020), p<0.001), preeclampsia (PE) (COR = 5.94, 95% CI (2.96-11.94), p<0.001), blood transfusion (COR = 14.11, 95% CI (2.50-79.65), p = 0.003), caesarian delivery (COR = 3.86, 95% CI (1.96-7.58), p<0.001) and male sex neonates (COR = 2.25, 95%CI (1.14-4.47), P = 0.020) presented with increased odds of LBW. Increasing gestational age at delivery presented with 28% reduced odds of LBW (COR = 0.72, 95% CI (1.12-4.40), P = 0.023). Upon controlling for potential confounders in multivariate logistic regression, only gestational age at delivery (AOR = 0.67, 95% CI (0.47-0.96), P = 0.030) remained significantly associated with reduced odds of LBW.
conclusionThis study found that high blood pressure at 1st visit, before and after delivery results in increased chances of delivering a baby with LBW. Furthermore, PTD<37 weeks, having PE in current pregnancy, and male sex potentiate the risk of LBW. On the other hand, increasing gestational age reduces the risk of LBW. Thus, we recommend that midwives should intensify education to pregnant women on the benefits of regular ANC visits to aid in the early detection of adverse foeto-maternal complications. We also recommend proper clinical management of pregnancies associated with an elevated blood pressure at registration. Also, maternal intrapartum blood pressure measurement could be used to predict LBW in low resourced settings.
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