SynthesisPLoS neglected tropical diseases2022
Community-level trachoma ecological associations and the use of geospatial analysis methods: A systematic review.
Synthesis in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of variables associated with snakebite risk in spatial and temporal analyses.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Pooled it
- Discrepancy Between Active Trachoma and Tests of Chlamydial Infection in Alto Amazonas, Peru.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Developing strategies to address persistent and recrudescent trachoma in Ethiopia using the Delphi techniques.International health · 2026Article
- National progress towards the elimination of trachomatous inflammation-follicular: analysis of 11 regions in Ethiopia.International health · 2026Article
- Trachoma Prevalence and Associated WASH and Behavioral Risk Among Rural Communities of North Gondar Zone, Ethiopia: A Community-Based Cross-Sectional Study.Journal of tropical medicine · 2026Article
- Using Model-Based Geostatistics to Refine Population-Based Estimates of Trachoma Prevalence: Update from a Technical Consultation.The American journal of tropical medicine and hygiene · 2025Article
- Understanding the impact of covariates for trachoma prevalence prediction using geostatistical methods.BMC global and public health · 2025Article
- Trachoma.Lancet (London, England) · 2025Review
- Correlates of Trachoma Recrudescence: Results from 51 District-Level Trachoma Surveillance Surveys in Amhara, Ethiopia.Tropical medicine and infectious disease · 2024Article
- Trachoma and the Importance of Sexual Infective Route in Developed Countries. Comment on Gallenga et al. Why the SAFE-Pathogens (Basel, Switzerland) · 2024Article
- Using model-based geostatistics for assessing the elimination of trachoma.PLoS neglected tropical diseases · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundTrachoma is targeted for global elimination as a public health problem by 2030. Understanding individual, household, or community-associated factors that may lead to continued transmission or risk of recrudescence in areas where elimination has previously been achieved, is essential in reaching and maintaining trachoma elimination. We aimed to identify climatic, demographic, environmental, infrastructural, and socioeconomic factors associated in the literature with trachoma at community-level and assess the strength of their association with trachoma. Because of the potential power of geospatial analysis to delineate the variables most strongly associated with differences in trachoma prevalence, we then looked in detail at geospatial analysis methods used in previous trachoma studies.
methodsWe conducted a systematic literature review using five databases: Medline, Embase, Global Health, Dissertations & Theses Global, and Web of Science, including publications from January 1950 to January 2021. The review protocol was prospectively registered with PROSPERO (CRD42020191718).
resultsOf 35 eligible studies, 29 included 59 different trachoma-associated factors, with eight studies also including spatial analysis methods. Six studies included spatial analysis methods only. Higher trachomatous inflammation-follicular (TF) prevalence was associated with areas that: had lower mean annual precipitation, lower mean annual temperatures, and lower altitudes; were rural, were less accessible, had fewer medical services, had fewer schools; and had lower access to water and sanitation. Higher trachomatous trichiasis (TT) prevalence was associated with higher aridity index and increased distance to stable nightlights. Of the 14 studies that included spatial methods, 11 used exploratory spatial data analysis methods, three used interpolation methods, and seven used spatial modelling methods.
conclusionResearchers and decision-makers should consider the inclusion and potential influence of trachoma-associated factors as part of both research activities and programmatic priorities. The use of geospatial methods in trachoma studies remains limited but offers the potential to define disease hotspots and areas of potential recrudescence to inform local, national, and global programmatic needs.
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