ArticleScience China. Life sciences2022
Molecular studies of cellulose synthase supercomplex from cotton fiber reveal its unique biochemical properties.
Article in Science China. Life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 59 citations in OpenAlex.
- Pan-Genome Analysis of theGenes · 2026Article
- Systems-level proteomic models of cotton fiber development: a high-resolution data resource to analyze cell dynamics and trait engineering.Plant physiology · 2026Article
- A Natural LTR Retrotransposon Insertion in the Promoter of GhNAC140-Dt Boosts Cotton Lint Yield.Plant biotechnology journal · 2026Article
- Identification of Key Genes for the Simultaneous Improvement of Fiber Strength and Lint Percentage inInternational journal of molecular sciences · 2026Article
- CRISPR/Cas9-Mediated Specific Knockout of GhCesA4/7/8 Improves Cotton Fibre Quality.Plant biotechnology journal · 2026Article
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- Natural fibers in sustainable materials: extraction technologies, fiber modification, and performance-sustainability relationships.RSC advances · 2026Review
- Biased retention and functional diversification of CESA superfamily genes in Medicago mediating development and abiotic stress responses.BMC plant biology · 2026Article
- NAC transcription factor GbNTL9 modifies the accumulation and organization of cellulose microfibrils to enhance cotton fiber strength.Journal of advanced research · 2025Article
- A ubiquitin-GhUBX-GhCDC48 module regulates secondary cell wall thickening in cotton fiber.Plant physiology · 2025Article
- Comparative transcriptome analysis unravels distinct regulatory mechanisms governing fiber development in red silk cotton tree (Bombax ceiba).BMC plant biology · 2025Article
- Upcycling Textile Waste into Anionic and Cationic Cellulose Nanofibrils and Their Assembly into 2D and 3D Materials.ChemSusChem · 2025Article
- GhMYB102 affects cotton fibre elongation and secondary wall thickening by regulating GhIRX10 in cotton.Plant biotechnology journal · 2025Article
- Water stress reduces cellulose deposition in the cell wall and increases wax content, resulting in decreased fiber quality.Frontiers in plant science · 2025Article
- GhCASPL1 regulates secondary cell wall thickening in cotton fibers by stabilizing the cellulose synthase complex on the plasma membrane.Journal of integrative plant biology · 2024Article
- Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development.Journal of advanced research · 2024Article
- How Many Glucan Chains Form Plant Cellulose Microfibrils? A Mini Review.Biomacromolecules · 2024Review
- A Genome-Wide Alternative Splicing Analysis ofPlants (Basel, Switzerland) · 2024Article
- A telomere-to-telomere cotton genome assembly reveals centromere evolution and a Mutator transposon-linked module regulating embryo development.Nature genetics · 2024Article
- Unraveling the lncRNA-miRNA-mRNA Regulatory Network Involved in Poplar Coma Development through High-Throughput Sequencing.International journal of molecular sciences · 2024Article
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8 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Cotton fiber is a highly elongated and thickened single cell that produces large quantities of cellulose, which is synthesized and assembled into cell wall microfibrils by the cellulose synthase complex (CSC). In this study, we report that in cotton (Gossypium hirsutum) fibers harvested during secondary cell wall (SCW) synthesis, GhCesA 4, 7, and 8 assembled into heteromers in a previously uncharacterized 36-mer-like cellulose synthase supercomplex (CSS). This super CSC was observed in samples prepared using cotton fiber cells harvested during the SCW synthesis period but not from cotton stem tissue or any samples obtained from Arabidopsis. Knock-out of any of GhCesA 4, 7, and 8 resulted in the disappearance of the CSS and the production of fiber cells with no SCW thickening. Cotton fiber CSS showed significantly higher enzyme activity than samples prepared from knock-out cotton lines. We found that the microfibrils from the SCW of wild-type cotton fibers may contain 72 glucan chains in a bundle, unlike other plant materials studied. GhCesA4, 7, and 8 restored both the dwarf and reduced vascular bundle phenotypes of their orthologous Arabidopsis mutants, potentially by reforming the CSC hexamers. Genetic complementation was not observed when non-orthologous CesA genes were used, indicating that each of the three subunits is indispensable for CSC formation and for full cellulose synthase function. Characterization of cotton CSS will increase our understanding of the regulation of SCW biosynthesis.
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