Evidence map›Paper›PMID 35394589›Full record

ArticleDigestive diseases and sciences2022

Consumption of Yeast-Fermented Wheat and Rye Breads Increases Colitis and Mortality in a Mouse Model of Colitis.

Julia Zimmermann, Luigia De Fazio, Valentina Kaden-Volynets, Bernd Hitzmann, Stephan C Bischoff

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. The MicroalgaeNutrients · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Julia ZimmermannDepartment of Nutritional Medicine/Prevention, University of Hohenheim, Fruwirthstrasse 12, 70599, Stuttgart, Germany.
Luigia De FazioDepartment of Medical and Surgical Science (DIMEC), University of Bologna, Via Massarenti 9, 40138, Bologna, Italy.
Valentina Kaden-VolynetsDepartment of Nutritional Medicine/Prevention, University of Hohenheim, Fruwirthstrasse 12, 70599, Stuttgart, Germany.
Bernd HitzmannDepartment of Process Analytics and Cereal Science, University of Hohenheim, Garbenstraße 23, 70599, Stuttgart, Germany.
Stephan C BischoffDepartment of Nutritional Medicine/Prevention, University of Hohenheim, Fruwirthstrasse 12, 70599, Stuttgart, Germany. bischoff.stephan@uni-hohenheim.de.ORCID 0000-0003-2614-5948
University of Hohenheim · DEUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCereals are known to trigger for wheat allergy, celiac disease and non-celiac wheat sensitivity (NCWS). Inflammatory processes and intestinal barrier impairment are suspected to be involved in NCWS, although the molecular triggers are unclear.

aimsWe were interested if different bread types influence inflammatory processes and intestinal barrier function in a mouse model of inflammatory bowel disease.

methodsEpithelial caspase-8 gene knockout (Casp8

resultsRegardless of the diet, Casp8

conclusionsBread components, especially those from yeast-fermented breads from wheat and rye, increase colitis and mortality in Casp8

Indexed as

BreadColitisAnimalsDiet, Gluten-FreeGlutensInflammationMiceSaccharomyces cerevisiaeSecaleGlutensBaker’s yeastBreadColitisInflammatory bowel diseaseWheat hypersensitivity

Identifiers

PMID35394589
PMCPMC9352744
OpenAlexW4225525012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.