Evidence map›Paper›PMID 35394552›Full record

ArticleLasers in medical science2022

Photobiomodulation Therapy Affects the Elastic Modulus, Cytoskeletal Rearrangement and Migration Capability of Human Osteosarcoma Cells.

Amin Barati Shoorche, Alireza Mohammadkarim, Majid Jadidi, Marjan Bahraminasab

Abstract read
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Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amin Barati ShoorcheDepartment of Medical Physics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Alireza MohammadkarimDepartment of Medical Physics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran. mohammadkarim.medphys@gmail.com.
Majid JadidiDepartment of Medical Physics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Marjan BahraminasabNervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Semnan University of Medical Sciences · IR

Funding

Semnan University of Medical Sciences 1709
6 · The paper itself

Abstract

Photobiomodulation (PBM) therapy utilizes low-power lasers to modulate the viability of living human cells and leads to changes in proliferation, differentiation, adhesion and gene expression, even though the rearrangement of cytoskeleton was not previously studied. The present study aims to evaluate the photobiological effects on the elastic behavior of human osteosarcoma cells (MG-63) and their morphological changes. Fluorescence staining, confocal imaging and atomic force microscopy (AFM) topography were performed to study the effects of PBM therapy with the exposure of 532 nm-25mW, 650 nm-3mW, 650 nm-150mW and 780 nm-70mW beams following the 5-min continuous irradiation. The area of each beam was 3.14cm

Indexed as

Low-Level Light TherapyOsteosarcomaCell ProliferationCytoskeletonElastic ModulusHumansAtomic force microscopyCell elasticityF-actin fibersMigration assayOsteosarcomaPhotobiomodulation

Identifiers

PMID35394552
OpenAlexW4225728401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.