ArticleAmerican journal of respiratory and critical care medicine2022
Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
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Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease.American journal of respiratory and critical care medicine · 2023Pooled it
- Proteomic study of high-altitude pulmonary hypertension in the Xinjiang Pamir highlanders.BMC pulmonary medicine · 2026Article
- Multi-Omics Identification of Biomarkers for High-Altitude Pulmonary Hypertension.Journal of cardiovascular development and disease · 2026Article
- Advances in the pathogenesis and clinical management of pulmonary hypertension.Medical review (2021) · 2026Review
- Genetic Evidence Reveals Causal Effect of Circulating Proteome on Random Glucose: A Mendelian Randomization Study.Journal of diabetes research · 2026Article
- Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment.Nature communications · 2025Article
- Protein biomarkers in pulmonary arterial hypertension: advances, clinical relevance, and translational challenges.Journal of translational medicine · 2025Review
- Lung Single-Cell Transcriptomics Reveal Diverging Pathobiology and Opportunities for Precision Targeting in Scleroderma-Associated Versus Idiopathic Pulmonary Arterial Hypertension.Circulation. Genomic and precision medicine · 2025Article
- Exploratory Study of Prognostic Plasma Biomarkers in Patients with Pulmonary Arterial Hypertension.The American journal of pathology · 2025Article
- Clustering Patients with Pulmonary Hypertension Using the Plasma Proteome.American journal of respiratory and critical care medicine · 2025Article
- State of the Art in Pulmonary Arterial Hypertension: Molecular Basis, Imaging Modalities, and Right Heart Failure Treatment.Biomedicines · 2025Review
- Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension.American journal of respiratory and critical care medicine · 2025Article
- Plasma proteins and herpes simplex virus infection: a proteome-wide Mendelian randomization study.Virus genes · 2025Article
- Article
- ARF6 as a Novel Activator of HIF-2α in Pulmonary Arterial Hypertension.American journal of respiratory cell and molecular biology · 2025Article
- Genetically predicted endogenous sex hormone levels with risk of eczema or dermatitis.Hormones (Athens, Greece) · 2025Article
- Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series).Pulmonary circulation · 2025Article
- A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation.American journal of physiology. Cell physiology · 2024Article
- Serum proteome profiling reveals HGFA as a candidate biomarker for pulmonary arterial hypertension.Respiratory research · 2024Article
- Circulating biomarkers in pulmonary arterial hypertension: State-of-the-art review and future directions.JHLT open · 2024Review
Corrections and comments
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Authors and funding
24 authors at 8 institutions in 4 countries.
Lars HarbaumNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0002-9422-6195
Christopher J RhodesNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
John WhartonNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
Allan LawrieDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, United Kingdom.ORCID 0000-0003-4192-9505
Jason H KarnesDepartment of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona.
Ankit A DesaiDepartment of Medical and Molecular Genetics, and Krannert Institute of Cardiology, Department of Medicine, Indiana University, Indianapolis, Indiana.
William C NicholsDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Marc HumbertUniversité Paris-Saclay, AP-HP, INSERM UMR_S 999, Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Centre, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
David MontaniUniversité Paris-Saclay, AP-HP, INSERM UMR_S 999, Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Centre, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.ORCID 0000-0002-9358-6922
Barbara GirerdUniversité Paris-Saclay, AP-HP, INSERM UMR_S 999, Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Centre, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
Olivier SitbonUniversité Paris-Saclay, AP-HP, INSERM UMR_S 999, Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Centre, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.ORCID 0000-0002-1942-1951
Mario BoehmDepartment of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany.
Tatyana NovoyatlevaDepartment of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany.
Ralph T SchermulyDepartment of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany.
H Ardeschir GhofraniDepartment of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany.
Mark ToshnerDepartment of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
David G KielyDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, United Kingdom.
Luke S HowardNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
Emilia M SwietlikDepartment of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Stefan GräfDepartment of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.ORCID 0000-0002-1315-8873
Maik PietznerComputational Medicine, Berlin Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Germany; and.
Nicholas W MorrellDepartment of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Martin R WilkinsNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-3926-1171
U.K. National Institute for Health Research BioResource Rare Diseases Consortium, U.K. Pulmonary Arterial Hypertension Cohort Study Consortium, and U.S. Pulmonary Arterial Hypertension Biobank Consortium
Imperial College London · GBUniversity of Cambridge · GBInserm · FRJustus-Liebig-Universität Gießen · DEUniversity of Sheffield · GBCincinnati Children's Hospital Medical Center · USIndiana University – Purdue University Indianapolis · USUniversity of Arizona · US
Funding
National Biological Sample and Data Repository for PAHR24HL105333 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI NICHOLS, WILLIAM C · 2012 to 2016
$10.1MPathogenic Role of IL-18 in Sickle Cell Cardiomyopathy and Inducible Ventricular TachycardiaR01HL136603 · NHLBI · UNIVERSITY OF ARIZONA · PI DESAI, ANKIT A · 2017 to 2021
$2.4MLeveraging the Microbiome, Local Admixture, and Machine Learning to Optimize Anticoagulant Pharmacogenomics in Medically Underserved PatientsR01HL158686 · NHLBI · UNIVERSITY OF ARIZONA · PI KARNES, JASON HANSEN · 2021 to 2025
$2.2MABO and Immunogenetic Variation in the Pathogenesis of Heparin-Induced ThrombocytopeniaR01HL156993 · NHLBI · UNIVERSITY OF ARIZONA · PI KARNES, JASON HANSEN · 2022 to 2025
$2.0MGenomic and Transcriptomic Influences on Heparin-Induced ThrombocytopeniaK01HL143137 · NHLBI · UNIVERSITY OF ARIZONA · PI KARNES, JASON HANSEN · 2019 to 2022
$615kBritish Heart Foundation CH/09/001/25945British Heart Foundation FS/13/48/30453British Heart Foundation FS/15/59/31839British Heart Foundation FS/18/52/33808British Heart Foundation RE/18/4/34215British Heart Foundation SP/12/12/29836British Heart Foundation SP/18/10/33975Department of HealthMedical Research Council MR/K020919/1NHLBI NIH HHS K01 HL143137NHLBI NIH HHS R01 HL136603NHLBI NIH HHS R01 HL156993NHLBI NIH HHS R01 HL158686NHLBI NIH HHS R24 HL105333
Abstract
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Indexed as
Hypertension, PulmonaryPulmonary Arterial HypertensionBlood ProteinsFamilial Primary Pulmonary HypertensionHumansNetrinsPathology, MolecularProteomeThrombospondinsBlood ProteinsNetrinsProteomeThrombospondinscase-control studiesgenomeMendelian randomizationprotein quantitative trait loci
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.