ArticleEJNMMI physics2022
EARL compliance measurements on the biograph vision Quadra PET/CT system with a long axial field of view.
Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 23 citations in OpenAlex.
- From sensitivity gain to clinical decisions: total-body and long-axial-field-of-view PET/CT for diagnosis and image-based management in oncology and systemic disease.Annals of nuclear medicine · 2026Review
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- One-day dual-tracer examination in neuroendocrine neoplasms: a real advantage of low activity LAFOV PET imaging.European journal of nuclear medicine and molecular imaging · 2025Article
- Optimisation of low and ultra-low dose scanning protocols for ultra-extended field of view PET in a real-world clinical setting.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- EARL compliance on the Biograph Vision Quadra PET-CT: phantom study for static and continuous bed motion acquisitions.Frontiers in nuclear medicine · 2025Article
- Clinical Performance Comparison of a Long Versus a Short Axial Field-of-View PET/CT Using EARL-Compliant Reconstructions.Molecular imaging and biology · 2024Article
- FDG imaging with long-axial field-of-view PET/CT in patients with high blood glucose-a matched pair analysis.European journal of nuclear medicine and molecular imaging · 2024Article
- Mitigating SUV uncertainties using total body PET imaging.European journal of nuclear medicine and molecular imaging · 2024Article
- A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design.EJNMMI physics · 2023Article
- Image Quality and Quantitative PET Parameters of Low-Dose [Diagnostics (Basel, Switzerland) · 2023Article
- Collection on total-body PET.EJNMMI physics · 2023Article
- Impact of the new ultra-high sensitivity mode in a long axial field-of-view PET/CT.Annals of nuclear medicine · 2023Article
- Application of the long axial field-of-view PET/CT with low-dose [European journal of nuclear medicine and molecular imaging · 2023Article
- A review of harmonization strategies for quantitative PET.Annals of nuclear medicine · 2023Review
- Total-body pediatric PET is ready for prime time.European journal of nuclear medicine and molecular imaging · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim was to determine sets of reconstruction parameters for the Biograph Vision Quadra (Siemens Healthineers) PET/CT system that result in quantitative images compliant with the European Association of Nuclear Medicine Research Ltd. (EARL) criteria. Using the Biograph Vision 600 (Siemens Healthineers) PET/CT technology but extending the axial field of view to 106 cm, gives the Vision Quadra currently an around fivefold higher sensitivity over the Vision 600 with otherwise comparable spatial resolution. Therefore, we also investigated how the number of incident positron decays-i.e., exposure-affects EARL compliance. This will allow estimating a minimal acquisition time or a minimal applied dose in clinical scans while retaining data comparability.
methodsWe measured activity recovery curves on a NEMA IEC body phantom filled with an aqueous
resultsUsing 6 iterations, 5 subsets and 7.8 mm Gauss filtering resulted in optimal EARL1 compliance and recovery curve monotonicity in all analyzed frames, except in the 3 s frames. Most robust EARL2 compliance and monotonicity were achieved with 2 iterations, 5 subsets, and 3.6 mm Gauss FWHM in frames with durations between 30 s and 10 min. RC
conclusionsWhile EARL1 compliance was robust over most exposure ranges, EARL2 compliance required exposures between 1.2 MDecays/ml to 11.5 MDecays/ml. The Biograph Vision Quadra's high sensitivity makes frames as short as 10 s feasible for comparable quantitative images. Lowering EARL2 RC
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