Evidence map›Paper›PMID 35394238›Full record

ArticleEJNMMI research2022

PET-CT imaging of pulmonary inflammation using [

Emmi Puuvuori, Francesco Liggieri, Irina Velikyan, Elena Chiodaroli, Jonathan Sigfridsson, Hampus Romelin, Sofie Ingvast, Olle Korsgren, Gry Hulsart-Billström, Gaetano Perchiazzi and 1 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective Role of Octreotide in Acute and Chronic Lung Injuries.International journal of preventive medicine · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. 2-deoxy-2-[Molecular imaging and biology · 2023
    Article
  8. PET Imaging of Neutrophil Elastase withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Emmi PuuvuoriScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, Dag Hammarskjölds väg 14C, 3tr, 751 83, Uppsala, Sweden.
Francesco LiggieriHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Irina VelikyanScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, Dag Hammarskjölds väg 14C, 3tr, 751 83, Uppsala, Sweden.
Elena ChiodaroliHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Jonathan SigfridssonHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Hampus RomelinHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Sofie IngvastDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Olle KorsgrenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Gry Hulsart-BillströmScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, Dag Hammarskjölds väg 14C, 3tr, 751 83, Uppsala, Sweden.
Gaetano PerchiazziHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Olof ErikssonScience for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, Dag Hammarskjölds väg 14C, 3tr, 751 83, Uppsala, Sweden. olof.eriksson@ilk.uu.se.ORCID http://orcid.org/0000-0002-2515-8790
Uppsala University · SE

Funding

Vetenskapsrådet 2020-02312
6 · The paper itself

Abstract

purposeIn the characterization of severe lung diseases, early detection of specific inflammatory cells could help to monitor patients' response to therapy and increase chances of survival. Macrophages contribute to regulating the resolution and termination of inflammation and have increasingly been of interest for targeted therapies. [

methodsInflammation in the pig lungs was induced by warm saline lavage followed by injurious ventilation in farm pigs (n = 7). Healthy pigs (n = 3) were used as control. A 60-min dynamic PET scan over the lungs was performed after [

resultsThe accumulation of [

conclusionThe feasibility of the noninvasive assessment of tissue macrophages using [

Indexed as

[68Ga]Ga-DOTA-TATEInflammation imagingLung inflammationMacrophagePET

Identifiers

PMID35394238
PMCPMC8994000
OpenAlexW4224317519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.