Evidence map›Paper›PMID 35393940›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Kleine-Levin syndrome: report of a case with marked dysautonomic features.

Giuseppe Fiamingo, Roberta Esposto, Beatrice Dal Fabbro, Michele Terzaghi

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Giuseppe FiamingoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Roberta EspostoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Beatrice Dal FabbroDepartment of Neurology, G. Salvini Hospital, Garbagnate Milanese, Italy.
Michele TerzaghiSleep Medicine Centre, IRCCS Mondino Foundation, Via Mondino, Pavia, Italy.
In-Q-Tel · USUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kleine-Levin syndrome is a rare neurologic disorder of unknown etiopathogenesis, characterized by abrupt onset and remission of attacks of hypersomnia and cognitive dysfunctions. Psychiatric symptoms are frequently present, ranging from disinhibited sexual behavior and eating disorders to hallucinations, anxiety, mood alterations, and derealization. A vast range of attack-related dysautonomic signs and symptoms are reported but remain poorly described. We describe a patient with Kleine-Levin syndrome with sleep attacks dominated by marked dysautonomic features. We briefly review similar clinical cases and suggest that the hypothalamus may play a central role in the genesis of autonomic dysfunction in Kleine-Levin syndrome. CITATION: Fiamingo G, Esposto R, Dal Fabbro B, Terzaghi M. Kleine-Levin syndrome: report of a case with marked dysautonomic features.

Indexed as

Disorders of Excessive SomnolenceFeeding and Eating DisordersKleine-Levin SyndromeSleep Wake DisordersHallucinationsHumanscentral autonomic networkdysautonomiahypersomniahypothalamusKleine-Levin syndrome

Identifiers

PMID35393940
PMCPMC9435349
OpenAlexW4223491870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.