Evidence map›Paper›PMID 35393933›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2022

HIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019.

Hendrik Streeck, Klaus Jansen, Trevor A Crowell, Allahna Esber, Heiko K Jessen, Christiane Cordes, Stefan Scholten, Stephan Schneeweiss, Norbert Brockmeyer, Christoph D Spinner and 12 more

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. German evidence- and consensus-based guideline on the management of penile urethritis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Guideline
  2. Article
  3. Article
  4. Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Prevalence ofSexually transmitted infections · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Frontiers in microbiology · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 11 institutions in 2 countries.

Hendrik StreeckInstitute of Virology, University Hospital, University of Bonn, Bonn, Germany.
Klaus JansenRobert Koch Institute, Berlin, Germany.
Trevor A CrowellU.S. Military HIV Research Program, Silver Spring, United States.
Allahna EsberU.S. Military HIV Research Program, Silver Spring, United States.
Heiko K JessenPrivate Practice Jessen+Jessen, Berlin, Germany.
Christiane CordesPrivate Practice Cordes, Berlin, Germany.
Stefan ScholtenPrivate Practice Hohenstaufenring, Cologne, Germany.
Stephan SchneeweissPrivate Practice Hohenstaufenring, Cologne, Germany.
Norbert BrockmeyerInterdisciplinary Immunological Outpatient Clinic, Center for Sexual Health and Medicine, Department of Dermatology, Venereology and Allergology, Ruhr University Bochum, Bochum, Germany.
Christoph D SpinnerTechnical University of Munich, School of Medicine, University Hospital Rechts der Isar, Department of Internal Medicine II, Munich, Germany.
Markus BickelInfektiologikum Frankfurt, Frankfurt, Germany.
Stefan EsserHPSTD clinic, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Jukka HartikainenPrivate Practice ZIBP, Berlin, Germany.
Albrecht StoehrInstitute for interdisciplinary medicine, Hamburg, Germany.
Clara LehmannUniversity of Cologne, Cologne, Germany.
Ulrich MarcusRobert Koch Institute, Berlin, Germany.
Jörg Janne VehreschildLaboratory Krone, Bad Salzuflen, Germany.
Alexandra KnorrInstitute of HIV Research, University Duisburg-Essen, Essen, Germany.
Anna-Lena BrillenInstitute of HIV Research, University Duisburg-Essen, Essen, Germany.
Carsten TiemannLaboratory Krone, Bad Salzuflen, Germany.
Merlin L RobbU.S. Military HIV Research Program, Silver Spring, United States.
Nelson L MichaelWalter Reed Army Institute of Research, Silver Spring, United States.
Henry M. Jackson Foundation · USUniversity of Duisburg-Essen · DELaboratory Krone · DERobert Koch Institute · DEGoethe University Frankfurt · DEInstitute for Interdisciplinary Medicine · DERuhr University Bochum · DETUM Klinikum · DEUniversity of Bonn · DEUniversity of Cologne · DEWalter Reed Army Institute of Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionDespite increased use of pre-exposure prophylaxis (PrEP) in Germany, HIV infection rates are not declining and little is known about how this prevention method affects the prevalence of sexually transmitted infections (STI) among men who have sex with men (MSM).AimWe studied, in a large multicentre cohort, STI point prevalence, co-infection rates, anatomical location and influence of PrEP.MethodsThe BRAHMS study was a prospective cohort study conducted at 10 sites in seven major German cities that enrolled MSM reporting increased sexual risk behaviour. At screening visits, MSM were tested for

Indexed as

Chlamydia InfectionsGonorrheaHIV InfectionsMycoplasma genitaliumPre-Exposure ProphylaxisSexual and Gender MinoritiesSexually Transmitted DiseasesChlamydia trachomatisGermanyHomosexuality, MaleHumansMaleNeisseria gonorrhoeaePrevalenceProspective StudiesChlamydiaMycoplasma genitalium, GonorrheaPre-Exposure ProphylaxisSexually Transmitted DiseasesSyphilis

Identifiers

PMID35393933
PMCPMC8991735
OpenAlexW4223572910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.