Evidence map›Paper›PMID 35393931›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2022

HIV-1-infection in a man who has sex with men despite self-reported excellent adherence to pre-exposure prophylaxis, the Netherlands, August 2021: be alert to emtricitabine/tenofovir-resistant strain transmission.

Jeffrey Cd Koole, Feline de la Court, Matthijs Ra Welkers, Kenneth Yap, Janneke E Stalenhoef, Suzanne Jurriaans, Henry Jc de Vries, Eline Lm Op de Coul, Maria Prins, Elske Hoornenborg

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jeffrey Cd KooleDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Feline de la CourtDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Matthijs Ra WelkersDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Kenneth YapDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Janneke E StalenhoefDepartment of Internal Medicine, OLVG, Amsterdam, the Netherlands.
Suzanne JurriaansDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, Amsterdam, the Netherlands.
Henry Jc de VriesDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Eline Lm Op de CoulCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Maria PrinsDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
Elske HoornenborgDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, the Netherlands.
GGD Amsterdam · NLAmsterdam University Medical Centers · NLNational Institute for Public Health and the Environment · NLOLVG · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In August 2021, a man who has sex with men was diagnosed with HIV-1 infection despite using event-driven pre-exposure prophylaxis for over 2 years with self-reported excellent adherence. Sequencing identified resistance-associated mutations (RAM) M184V and K65R, conferring resistance to emtricitabine and tenofovir, and RAM V108I and E138A. Background RAM prevalence was two of 164 (1.2%) new HIV diagnoses in Amsterdam (2017-19). We reiterate the need for frequent HIV testing among PrEP users and additional testing in case of symptoms.

Indexed as

Anti-HIV AgentsHIV-1HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesEmtricitabineHomosexuality, MaleHumansMaleMedication AdherenceNetherlandsSelf ReportTenofovirAnti-HIV AgentsEmtricitabineTenofovirantiretroviral drug resistancecase reportdiagnosticsgenomic surveillanceHIVHIV pre-exposure prophylaxisprevention

Identifiers

PMID35393931
PMCPMC8991733
OpenAlexW4223452679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.