ArticleAnnals of clinical and translational neurology2022
Prevalence and patterns of symptoms of dysautonomia in patients with long-COVID syndrome: A cross-sectional study.
Article in Annals of clinical and translational neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05993871 (Diabetic Small Fiber Neuropathy), which is not on this map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study
Who cites it
31 citing papers in PubMed.
- Plasma Cytokine and Caspase-1p20 Profiles in Pre-Pandemic and Long COVID-Associated Postural Orthostatic Tachycardia Syndrome.Biomedicines · 2026Article
- Dysautonomia in Long COVID: Why Sex Differences Matter in Cardiovascular Risk Assessment.Clinical medicine & research · 2026Article
- Author Response to "Dysautonomia in Long COVID: Why Sex Differences Matter in Cardiovascular Risk Assessment".Clinical medicine & research · 2026Article
- Development of the long COVID - 6 dimensions quality of life (LC-6D-QoL) scale: a Delphi study.Journal of patient-reported outcomes · 2026Article
- Orthostatic Tachycardia-Hypotensive Syndrome: A Novel Form of Orthostatic Intolerance in the Young.Pediatric cardiology · 2026Article
- Validation of the Arabic version of the composite autonomic symptom score 31 questionnaire in diabetic autonomic neuropathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Dysautonomia in Long COVID is Prevalent and Could Explain the Frequency of Symptoms.Clinical medicine & research · 2026Article
- Mechanisms and impact of long COVID: pathophysiology, neuropsychiatric effects and vaccination.Frontiers in immunology · 2026Review
- Autonomic dysfunction and quality of life in a cohort of neurology outpatients with post-acute sequelae of COVID-19, a two-year follow-up study.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2026Article
- Long-Term Manifestations of COVID-19: A Review.Cureus · 2025Review
- Re-engineering a machine learning phenotype to adapt to the changing COVID-19 landscape: a machine learning modelling study from the N3C and RECOVER consortia.The Lancet. Digital health · 2025Article
- The prevalence of orthostatic intolerance, postural orthostatic tachycardia syndrome and orthostatic hypotension in post-acute sequelae of COVID-19.Frontiers in cardiovascular medicine · 2025Review
- The Diagnostic Journey of Dysautonomia Patients: Insights from a Patient-Reported Outcome Study.Journal of patient experience · 2025Article
- Letter to the Editor: SARS-CoV-2-Related Polyradiculitis Requires Exclusion of Alternative Causes and Long-Term Follow-up.Journal of Korean medical science · 2024Article
- Recovery of neurophysiological measures in post-COVID fatigue: a 12-month longitudinal follow-up study.Scientific reports · 2024Article
- Post-COVID dysautonomias: what we know and (mainly) what we don't know.Nature reviews. Neurology · 2024Review
- A MULTI-HIT MODEL OF LONG COVID PATHOPHYSIOLOGY: THE INTERACTION BETWEEN IMMUNE TRIGGERS AND NERVOUS SYSTEM SIGNALING.Transactions of the American Clinical and Climatological Association · 2024Article
- SARS-CoV-2 Infection Impairs Oculomotor Functions: A Longitudinal Eye-tracking Study.Journal of eye movement research · 2024Article
- Postural orthostatic tachycardia syndrome after COVID-19 vaccination.Heart rhythm · 2024Article
- Resonant breathing improves self-reported symptoms and wellbeing in people with Long COVID.Frontiers in rehabilitation sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between autonomic dysfunction and long-COVID syndrome is established. However, the prevalence and patterns of symptoms of dysautonomia in long-COVID syndrome in a large population are lacking.
objectiveTo evaluate the prevalence and patterns of symptoms of dysautonomia in patients with long-COVID syndrome.
methodsWe administered the Composite Autonomic Symptom Score 31 (COMPASS-31) questionnaire to a sample of post-COVID-19 patients who were referred to post-COVID clinic in Assiut University Hospitals, Egypt for symptoms concerning for long-COVID syndrome. Participants were asked to complete the COMPASS-31 questionnaire referring to the period of more than 4 weeks after acute COVID-19.
resultsWe included 320 patients (35.92 ± 11.92 years, 73% females). The median COMPASS-31 score was 26.29 (0-76.73). The most affected domains of dysautonomia were gastrointestinal, secretomotor, and orthostatic intolerance with 91.6%, 76.4%, and 73.6%, respectively. There was a positive correlation between COMPASS-31 score and long-COVID duration (p < 0.001) and a positive correlation between orthostatic intolerance domain score and post-COVID duration (p < 0.001). There was a positive correlation between orthostatic intolerance domain score and age of participants (p = 0.004). Two hundred forty-seven patients (76.7%) had a high score of COMPASS-31 >16.4. Patients with COMPASS-31 >16.4 had a longer duration of long-COVID syndrome than those with score <16.4 (46.2 vs. 26.8 weeks, p < 0.001).
conclusionsSymptoms of dysautonomia are common in long-COVID syndrome. The most common COMPASS-31 affected domains of dysautonomia are gastrointestinal, secretomotor, and orthostatic intolerance. There is a positive correlation between orthostatic intolerance domain score and patients' age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.