Evidence map›Paper›PMID 35393704›Full record

ReviewThe European journal of neuroscience2022

Sex-dependent impact of microbiota status on cerebral μ-opioid receptor density in fischer rats.

Felix Effah, Nívea Karla de Gusmão Taveiros Silva, Katie Vijayanathan, Rosana Camarini, Fatima Joly, Benjamin Taiwo, Sylvie Rabot, Gaëlle Champeil-Potokar, Vincent Bombail, Alexis Bailey

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The European journal of neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Felix EffahPharmacology Section, St George's University of London, London, UK.ORCID 0000-0001-5623-914X
Nívea Karla de Gusmão Taveiros SilvaPharmacology Department, Universidade de Sao Paulo, São Paulo, Brazil.
Katie VijayanathanPharmacology Section, St George's University of London, London, UK.
Rosana CamariniPharmacology Department, Universidade de Sao Paulo, São Paulo, Brazil.
Fatima JolyUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France.
Benjamin TaiwoPharmacology Section, St George's University of London, London, UK.ORCID 0000-0002-3141-1027
Sylvie RabotUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France.
Gaëlle Champeil-PotokarUMR PNCA, AgroParisTech, INRAE, Université Paris-Saclay, Paris, France.
Vincent BombailUMR PNCA, AgroParisTech, INRAE, Université Paris-Saclay, Paris, France.ORCID 0000-0003-3313-2854
Alexis BaileyPharmacology Section, St George's University of London, London, UK.ORCID 0000-0003-1541-1964
AgroParisTech · FRSt George's, University of London · GBUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

μ-opioid receptors (MOPr) play a critical role in social play, reward and pain, in a sex- and age-dependent manner. There is evidence to suggest that sex and age differences in brain MOPr density may be responsible for this variability; however, little is known about the factors driving these differences in cerebral MOPr density. Emerging evidence highlights gut microbiota's critical influence and its bidirectional interaction with the brain on neurodevelopment. Therefore, we aimed to determine the impact of gut microbiota on MOPr density in male and female brains at different developmental stages. Quantitative [

Indexed as

MicrobiotaReceptors, Opioid, muAnalgesics, OpioidAnimalsFemaleMalePilot ProjectsProsencephalonRatsRats, Inbred F344Analgesics, OpioidReceptors, Opioid, mugerm-freemicrobiotaopioid receptorsrat brainreceptor ontogeny

Identifiers

PMID35393704
PMCPMC9324823
OpenAlexW4224237839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.