Evidence map›Paper›PMID 35393592›Full record

ArticleNature immunology2022

Replicative history marks transcriptional and functional disparity in the CD8

Kaspar Bresser, Lianne Kok, Arpit C Swain, Lisa A King, Laura Jacobs, Tom S Weber, Leïla Perié, Ken R Duffy, Rob J de Boer, Ferenc A Scheeren and 1 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Design principles of the cytotoxic CD8Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Review
  6. Article
  7. Design principles of the cytotoxic CD8bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. A variational deep-learning approach to modeling memory T cell dynamics.bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Kaspar Bresser *Division of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-7113-0476
Lianne Kok *Division of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-0445-7548
Arpit C SwainTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands.ORCID http://orcid.org/0000-0002-7816-1053
Lisa A KingDivision of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Laura JacobsDivision of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Tom S WeberThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Leïla PeriéInstitut Curie, Université PSL, Sorbonne Université, CNRS UMR168, Laboratoire Physico Chimie Curie, Paris, France.ORCID http://orcid.org/0000-0003-0798-4498
Ken R DuffyHamilton Institute, Maynooth University, Maynooth, Ireland.ORCID http://orcid.org/0000-0001-5587-9356
Rob J de BoerTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands.ORCID http://orcid.org/0000-0002-2130-691X
Ferenc A ScheerenDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands. f.a.scheeren@lumc.nl.ORCID http://orcid.org/0000-0002-8304-9023
Ton N SchumacherDivision of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. t.schumacher@nki.nl.ORCID http://orcid.org/0000-0003-0517-8804
The Netherlands Cancer Institute · NLLeiden University Medical Center · NLUtrecht University · NLCentre National de la Recherche Scientifique · FRNational University of Ireland, Maynooth · IEThe University of Melbourne · AU

Funding

European Research Council 268733
6 · The paper itself

Abstract

Clonal expansion is a core aspect of T cell immunity. However, little is known with respect to the relationship between replicative history and the formation of distinct CD8

Indexed as

CD8-Positive T-LymphocytesImmunologic Memory

Identifiers

PMID35393592
PMCPMC7612726
OpenAlexW4226051117

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.