Evidence map›Paper›PMID 35393334›Full record

ReviewJournal of medical genetics2022

Practice guidelines for

Daria Grafodatskaya, Darren D O'Rielly, Karine Bedard, Darci T Butcher, Christopher J Howlett, Alice Lytwyn, Elizabeth McCready, Jillian Parboosingh, Elizabeth L Spriggs, Andrea K Vaags and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of medical genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Prevalence of BRCA1/2 Mutation in High-Grade Non-Mucinous Ovarian Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2025
    Observational
  4. Review
  5. Article
  6. Review
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Daria Grafodatskaya *Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-4246-7675
Darren D O'Rielly *Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.
Karine BedardDépartement de Pathologie et Biologie cellulaire, Université de Montréal, Montreal, Québec, Canada.
Darci T ButcherDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Christopher J HowlettDepartment of Pathology and Laboratory Medicine, Schulich School of Medicine & Dentistry, Wester University, London, Ontario, Canada.
Alice LytwynDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Elizabeth McCreadyDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Jillian ParboosinghDepartment of Medical Genetics, Alberta Children's Hospital Research Institute for Child and Maternal Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Elizabeth L SpriggsGenomics, Diagnostic Services, Shared Health Manitoba, Winnipeg, Manitoba, Canada.
Andrea K VaagsLaboratory Medicine and Genetics, Trillium Health Partners, Mississauga, Ontario, Canada.
Tracy L StockleyDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada tracy.stockley@uhn.ca.ORCID 0000-0002-4476-9722
Hamilton Regional Laboratory Medicine Program · CALaboratoire de Biologie et Modélisation de la Cellule · FRManitoba Health · CAMemorial University of Newfoundland · CAUniversity Health Network · CAUniversity of Calgary · CAUniversity of Toronto · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this document is to provide pre-analytical, analytical and post-analytical considerations and recommendations to Canadian clinical laboratories developing, validating and offering next-generation sequencing (NGS)-based

Indexed as

Clinical Laboratory ServicesOvarian NeoplasmsBRCA1 ProteinBRCA2 ProteinCanadaCarcinoma, Ovarian EpithelialFemaleGenetic TestingGerm-Line MutationHigh-Throughput Nucleotide SequencingHumansBRCA1 ProteinBRCA1 protein, humanBRCA2 Proteingeneticsgenetics, medicalgenetic testinggerm-line mutationloss of function mutation

Identifiers

PMID35393334
PMCPMC9340048
OpenAlexW4225740878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.