ReviewJournal of the American College of Cardiology2022
Sex-Specific Considerations in the Presentation, Diagnosis, and Management of Ischemic Heart Disease: JACC Focus Seminar 2/7.
Review in Journal of the American College of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial.BMJ (Clinical research ed.) · 2022Trial
- Differences of plaque burden measures on CCTA in younger men and women.American journal of preventive cardiology · 2026Article
- Mitochondria-transplanted macrophages: a novel strategy targeting mitochondrial dysfunction to enhance myocardial repair after myocardial infarction.MedScience · 2026Article
- Sex- and race/ethnic differences in short- and long-term mortality after hospitalization for incident acute myocardial infarction.American heart journal plus : cardiology research and practice · 2026Article
- Sex-Related Differences in the Prevalence and Clinical Outcomes of Moderate-to-Severe Coronary Artery Calcification in Patients Undergoing Percutaneous Coronary Intervention.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
- Invisible Scar: Why Pregnancy History Matters for Women's Cardiovascular Health.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Incorporating angina into the HOpen heart · 2026Article
- New Risk Factor-Weighted Clinical Likelihood (RF-CL) in Diagnosis of Chronic Coronary Syndrome in Men and Women: Our First Impressions About the Differences and Opportunities.Journal of clinical medicine · 2026Article
- Sex-specific insights in atherosclerosis and pulmonary arterial hypertension: an overlooked comorbidity.Frontiers in cardiovascular medicine · 2026Review
- Sex-Based Differences in Long-Term Outcomes Following Intravascular Brachytherapy for In-Stent Restenosis.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Sex Differences in Atherosclerotic Coronary Artery Disease Patterns.Journal of the American Heart Association · 2025Article
- Protective effects and mechanisms of Saikosaponin A against myocardial ischemia based on network pharmacology, molecular docking, and experimental validation.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Endothelial Dysfunction in Sex-Specific Disparities in Cardiovascular Diseases: Biological Mechanisms, Diagnostic-Therapeutic Differences, and Translational Medicine Strategies.Reviews in cardiovascular medicine · 2025Review
- Correlation Between Coronary Artery Disease Severity Detected by CT Coronary Angiography and Grade of Left Ventricular Diastolic Dysfunction Detected by Echocardiography.Journal of clinical medicine · 2025Article
- Sex-Stratified Long-Term Outcome After Percutaneous Coronary Intervention: A Pooled Analysis of the SORT OUT All-Comer Trials.Journal of the American Heart Association · 2025Observational
- Role and research progress of histone modification in cardiovascular diseases (Review).Experimental and therapeutic medicine · 2025Review
- The Impact of Artificial Intelligence on Women's Cardiovascular Disease Care.Current cardiology reports · 2025Review
- The burden of ischemic heart disease among women of childbearing age in China from 1990 to 2021, and projections for the next 15 years.BMC women's health · 2025Article
- Trends and predictions of the global burden of ischemic heart disease in women of childbearing age attribute to high body mass index and hypertension,1990-2021: a systematic analysis for the Global Burden of Disease Study.BMC cardiovascular disorders · 2025Article
- The Fallibility of the Female Heart: A Patient's Perspective.JACC. Case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
There are sex-related differences in the epidemiology, presentation, diagnostic testing, and management of ischemic heart disease in women compared with men. The adjusted morbidity and mortality are persistently higher, particularly in younger women and Blacks. Women have more angina but less obstructive coronary artery disease, which affects delays in presentation and diagnosis and testing accuracy. The nonbiological factors play a significant role in access to care, ischemic heart disease management, and guideline adherence. Future research focus includes sex-specific outcomes, characterization of the biological differences, and implementation science around quality of clinical care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.