Evidence map›Paper›PMID 35392855›Full record

ArticleBMC pediatrics2022

Evaluation of the applicability of the current CDC pediatric ventilator-associated events (PedVAE) surveillance definition in the neonatal intensive care unit population.

Novisi Arthur, Ishminder Kaur, Alison J Carey

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07240038 (Evaluation of an Evidence Based, Bundled Intervention to Reduce Incidence of Ventilator-associated Pneumonia in Neonatal Units), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07240038 recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of an Evidence Based, Bundled Intervention to Reduce Incidence of Ventilator-associated Pneumonia in Neonatal Units (INBERNAV-Neo)

Typeobservational_patient_registrySponsorBiobizkaia Health Research InstituteRan2024 to 2026Enrolled1,500ConditionsPneumonia Ventilator Associated, Pneumonia Neonatal, Healthcare-associated InfectionsArmsMultimodal intervention to reduce the incidence of ventilator-associated pneumonia by training the health care team in specific and general evidence-based good clinical practices., Technique with a blind-protected catheter
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Novisi ArthurDivision of Neonatology, St. Christopher's Hospital for Children, Philadelphia, USA.
Ishminder KaurDivision of Infectious Diseases, Department of Pediatrics, University of California Los Angeles, Los Angeles, USA.
Alison J CareyDivision of Neonatology, St. Christopher's Hospital for Children, Philadelphia, USA. ajc327@drexel.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited data on pediatric ventilator-associated events (PedVAE) in the neonatal intensive care unit (NICU) setting, since the CDC mandated state reporting of these events in January 2019. This study sought to describe PedVAE rates and characteristics in the NICU population.

methodsSingle-center case-control study of infants requiring mechanical ventilation in a 39-bed level IV NICU between January 1, 2018 and December 31, 2020. Baseline infant demographic, respiratory support and antibiotic use data was obtained and comparisons were performed between patients with potential PedVAEs and those without events.

resultTwo hundred and nine infants were mechanically ventilated. Two of the 126 patients ventilated for ≥4 days met CDC criteria for PedVAEs with a total of 3 events, and 32 (25%) received antibiotics with escalation of respiratory support, primarily for tracheitis.

conclusionNICU-specific data on PedVAE is limited. Only 2 infants in the study period met the current CDC criteria for PedVAE with a rate of 0.9 events per 1000 ventilator days. The current CDC PedVAE definition might be inadequate to identify actionable VAEs to inform prevention efforts in the NICU population, and alternate indices could better characterize these events.

Indexed as

Intensive Care Units, NeonatalPneumonia, Ventilator-AssociatedAnti-Bacterial AgentsCase-Control StudiesCenters for Disease Control and Prevention, U.S.ChildHumansInfantInfant, NewbornRespiration, ArtificialUnited StatesVentilators, MechanicalAnti-Bacterial AgentsMechanical ventilationNeonatal intensive care unitNeonatePediatric ventilator-associated events

Identifiers

PMID35392855
PMCPMC8988311

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.