Observational studyBMC geriatrics2022
The impact of intravenous iron supplementation in elderly patients undergoing major surgery.
Observational study in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Prevalence of iron deficiency in patients admitted to a geriatric unit: a multicenter cross-sectional study.BMC geriatrics · 2024Trial
- Transfusion Practice in Elderly Surgical Patients in Germany-A Secondary Data Analysis of over 21 Million Patients over a Decade.Medicina (Kaunas, Lithuania) · 2026Article
- Perioperative Anemia, Transfusion Practices, and Patient Blood Management: Lessons from the COVID-19 Pandemic.Hematology reports · 2026Review
- Unmasking anemia in the elderly: A systematic review of prevalence, causes, and consequences.Journal of family medicine and primary care · 2025Review
- The Impact of Postoperative Intravenous Iron Therapy on Clinical Outcomes in Surgical Patients with Iron-Deficiency Anemia: A Comparative Analysis by Frailty Status in the Setting of Elective Cardiac Surgery.Medicina (Kaunas, Lithuania) · 2025Article
- Evaluation of postoperative results after a presurgical optimisation programme.Perioperative medicine (London, England) · 2024Article
- [Etiology and evolution of anemia in patients submitted to cardiovascular surgery].Archivos de cardiologia de Mexico · 2024Article
- SucrosomialPharmaceuticals (Basel, Switzerland) · 2023Review
- Impact of preoperative anemia, iron-deficiency and inflammation on survival after colorectal surgery-A retrospective cohort study.PloS one · 2022Article
- Association between preoperative anemia optimization and major complications after non-cardiac surgery: a retrospective analysis.Brazilian journal of anesthesiology (Elsevier)Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAge and preoperative anaemia are risk factors for poor surgical outcome and blood transfusion. The aim of this study was to examine the effect of iron supplementation in iron-deficient (ID) elderly patients undergoing major surgery.
methodIn this single-centre observational study, patients ≥ 65 years undergoing major surgery were screened for anaemia and ID. Patients were assigned to the following groups: A
resultsOf 4,381 patients screened at the anaemia walk-in clinic, 2,381 (54%) patients were ≥ 65 years old and 2,191 cases were included in analysis. The ID prevalence was 63% in patients with haemoglobin (Hb) < 8 g/dl, 47.2% in patients with Hb from 8.0 to 8.9 g/dl, and 44.3% in patients with Hb from 9 to 9.9 g/dl. In severely anaemic patients, an Hb increase of 0.6 (0.4; 1.2) and 1.2 (0.7; 1.6) g/dl was detected with iron supplementation 6-10 and > 10 days before surgery, respectively. Hb increased by 0 (-0.1; 0) g/dl with iron supplementation 1-5 days before surgery, 0.2 (-0.1; 0.5) g/dl with iron supplementation 6-10 days before surgery, and 0.2 (-0.2; 1.1) g/dl with supplementation > 10 days before surgery (p < 0.001 for 1-5 vs. 6-10 days). Overall, 58% of A
conclusionsIntravenous iron supplementation increases Hb level and thereby reduces blood transfusion rate in elderly surgical patients with ID anaemia.
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