ArticleBMC microbiology2022
Analysis of endophyte diversity of two Gentiana plants species and the association with secondary metabolite.
Article in BMC microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.Microbial cell factories · 2026Review
- Divergence of DioeciousMicroorganisms · 2026Article
- Analysis of endophytic bacteria diversity between two species of genus Polygala with similar medicinal value.Scientific reports · 2026Article
- Seasonal variations and assembly patterns of endophytic communities of Rheum palmatum.BMC microbiology · 2026Article
- Chemical Signaling and Metabolomic Crosstalk in Endophytic Fungi-Medicinal Plant Symbioses for Natural Product Discovery and Sustainable Bioproduction.Metabolites · 2026Review
- Review
- Diversity, Isolation and Bioactive Secondary Metabolites of Endophytic Fungi in Duchesnea indica (Andr.) Focke.Current microbiology · 2025Article
- Community Distribution of Endophytic Bacteria in Nodules of Vicia villosa in Rocky Desertification Area of Southwest China.Current microbiology · 2025Article
- Diversity and correlation analysis of microbiomes and metabolites of Sphagnum palustre in various microhabitats.BMC plant biology · 2025Article
- Diversity of endophytic bacteria in Paris Polyphylla var. yunnanensis and their correlation with polyphyllin content.BMC microbiology · 2025Article
- Analysis of endophytic bacterial diversity ofFrontiers in microbiology · 2025Article
- Endophytic bacteria: a sustainable strategy for enhancing medicinal plant cultivation and preserving microbial diversity.Frontiers in microbiology · 2024Review
- Exogenous and Endophytic Fungal Communities ofACS omega · 2023Article
- An integrated strategy for quality control of the multi-origins herb medicine of Gentianae Macrophyllae Radix based on UPLC-Orbitrap-MS/MS and HPLC-DAD.RSC advances · 2023Article
- Microbial fortification of pharmacological metabolites in medicinal plants.Computational and structural biotechnology journal · 2023Review
- The Endophytic Fungi Diversity, Community Structure, and Ecological Function Prediction ofMicroorganisms · 2022Article
- Dendrobine biosynthesis inFrontiers in microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe influence of external environmental factors on secondary metabolites of medicinal plants has always been studied. However, little is known about the relationships between endophytes and host metabolites, especially the relationship differences between different plant species. Thus, we used high-throughput sequencing methods to compare endophyte diversity from roots of two closely related species, Gentiana officinalis and G. siphonantha, from the same production area, and analyze the association with four secondary metabolites (Gentiopicroside, Loganic acid, Swertiamarine and Sweroside).
resultsThe fungal and bacteria communities' richness and diversity of G. siphonantha was higher than G. officinalis. Ascomycota and Proteobacteria were dominant fungal and bacterial phylum of the two closely related species. At the genus level, Tetracladium and Cadophora were dominant fungal genus in G. officinalis and G. siphonantha samples, respectively. While Pseudomonas was dominant bacterial genus in two closely related species, with relative abundances were 8.29 and 8.05%, respectively. Spearman analysis showed that the content of loganic acid was significantly positively correlated with endophytic fungi, the content of gentiopicroside, swertiamarine and sweroside were significantly positively correlated with endophytic bacteria in the two related species. PICRUSt and FUNGuild predictive analysis indicated that metabolism and saprotroph was primary function of endophytic bacteria and fungi in the two related species.
conclusionOur results will expand the knowledge on relationships of plant-microbe interactions and offer pivotal information to reveal the role of endophytes in the production of Gentiana plant and its important secondary metabolite.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.