Evidence map›Paper›PMID 35392640›Full record

ArticleSankhya. Series B (2008)2021

Shape Detection using Semi-parametric Shape-Restricted Mixed Effects Regression Spline with Applications.

Qing Yin, Xiaoshuang Xun, Shyamal D Peddada, Jennifer J Adibi

Open access · greenAbstract read
In one paragraph

Article in Sankhya. Series B (2008), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qing YinDepartment of Biostatistics, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261 USA.
Xiaoshuang XunDepartment of Epidemiology, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261 USA.
Shyamal D PeddadaDepartment of Biostatistics, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261 USA.
Jennifer J AdibiDepartment of Epidemiology, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261 USA.
University of Pittsburgh · US

Funding

Placental origins of phthalate-induced changes in fetal reproductive developmentR01ES029336 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ADIBI, JENNIFER JOAN · 2018 to 2023
$3.5M
NIEHS NIH HHS R01 ES029336
6 · The paper itself

Abstract

Linear models are widely used in the field of epidemiology to model the relationship between placental-fetal hormone and fetal/infant outcome. When researchers suspect curvilinear relationship exists, some nonparametric techniques, including regression splines, smoothing splines and penalized regression splines, can be used to model the relationship (Korevaar et al. 2016; Wu and Zhang 2006). By applying these nonparametric techniques, researchers can relax the linearity assumption and capture scientifically meaningful or appropriate shapes. In this paper, we focus on the regression spline technique and develop a method to help researchers select the most suitable shape to describe their data among increasing, decreasing, convex and concave shapes. Specifically, we develop a mixed effects regression spline to model hormonal data described in this paper. The proposed methodology is general enough to be applied to other similar problems. We illustrate the method using a state-wide prenatal screening program data set.

Indexed as

Mixed effects modelRegression splineShape-restricted

Identifiers

PMID35392640
PMCPMC8986130
OpenAlexW3132986641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.